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Hajdúch Marián M.D., Ph.D.

Journals

FLEUTI, M., T. SANCHEZ-QUIRANTE, L. POSTOVA SLAVETINSKA, E. TLOUŠŤOVÁ, M. TICHÝ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK
Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega. 2024, 9(18), 20557-20570, ISSN: 2470-1343, PMID: 38737052,  PDF.
Pooling of samples to optimise SARS-CoV-2 detection in nasopharyngeal swabs and gargle lavage self-samples for covid-19 diagnostics and surveillance. Infectious Diseases. 2024, 1-12, ISSN: 2374-4243, PMID: 38549542.
DAS, V., J. MILLER, C. ALLADI, N. ANNADURAI, J. DE SANCTIS, L. HRUBÁ, M. HAJDÚCH
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies. Medicinal Research Reviews. 2024, ISSN: 0198-6325, PMID: 38530106,

Books & book chapters

Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Predictive Cancer Biomarkers: Current Practice and Future Challenges, 1.vyd, Boca Raton, CRC Press, 2019, 7.5, 383-394, ISBN: 978-1-4987-6258-8,
BOUCHALOVÁ, K., M. HAJDÚCH, J. BOUCHAL, A. HLOBILKOVA, M. HOUDOVÁ MEGOVÁ, M. HUDCOVÁ, V. KOUDELÁKOVÁ, J. MEDALOVA, J. SROVNAL, R. TROJANEC
Prediktivní a prognostická onkologie, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2016, 122 s, Dedication: CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3188-8,

Intellectual property

SONIC HEDGEHOG (Urban)
  1. Patent: CZ 309885. Granted: 30.11.2023. Ownership: Palacký University Olomouc. Inventors: URBAN Milan, FRYDRYCH Ivo, BORKOVÁ Lucie, VRÁNOVÁ Barbora, HAJDÚCH Marián

Status: Available

HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS (Voller)
  1. Published Application: PV 2022-227 (13.12.2023). Ownership: Palacký University Olomouc, Institute of Physiology CAS. Inventors: VOLLER Jiří, MIK Václav, DOKONALOVÁ Markéta, SLÁDEK Martin, SUMOVÁ Alena, HAJDÚCH Marián, STRNAD Miroslav. 
  2. Published Application: PCT/CZ2023/050029 under WO 2023/232171 (7.12.2023)

Status: Patent pending; Available

RNA ISOLATION KIT (Džubák)

Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, GURSKÁ Soňa, KOUDELÁKOVÁ Vladimíra, JAWOREK Hana.

Status: Available

Postdoctoral mentorship

Dvořanová Štěpánková Jana Ph.D.

Novel Carborane Based Inhibitors of Carbonic Anhydrase IX

Status: Graduated.
Varanasi Lakshman Ph.D.

Identification and validation of serum-based biomarkers of gastrointestinal cancer in a mouse xenograft model

Status: Graduated.
Agrawal Khushboo Ph.D.

Status: Graduated.

Doctoral mentorship

Ondra Martin Ph.D.

Development and validation of luminescent HTS tool for discovery and optimization of novel combination of CFTR correctors and modifiers

Status: Graduated from 2017 to 2024.
Ziaei Nikta

Preparation of 3D cultures for high-throughput screening

Status: Ongoing from 2023.
Kubíčková Agáta Ph.D.

Role of transcription factor c-Myc in proliferation, quiscence, apoptosis and ribosomal biogenesis

Status: Graduated from 2016 to 2024.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Supervisors: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Biologically active molecules and their therapeutic combinations
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training