Mistrík Martin Ph.D.

User picture
Phone: +420 585634873
Groups: IMTM, LIG, STAFF

About me

Specializing in cellular stresses and their link to cancer development and treatment. Another specialization includes advanced microscopic techniques (the head of the bioimaging core facility: https://imtm.cz/core-facilities/bioimaging-core-facility ). Actively participated in the research of more than 10 national and international projects. Published more than >40 original investigations and three patents, >3000 citations, H-index 24

Journals

LACEY, M., L. BÉRESOVÁ, A. SROVNALOVÁ, P. POLISHCHUK, M. SALA, Z. ŠKROTT, M. HAJDÚCH, P. DŽUBÁK, J. BÁRTEK, A. ŠIŠKOVÁ, M. LÖFFELMANN, R. NENCKA, M. MISTRÍK
Autophagy revealed as a targetable vulnerability in senescent cells by cell painting phenotypic profiling: a mechanistic study of MCOPPB and related compounds. Geroscience. 2026, ISSN: 2509-2723, PMID: 42062708,  PDF.
VALKOVA, L., L. SUCHANKOVA HOCHVALDOVA, M. MISTRÍK, M. KOLÁŘ, K. LANGOVÁ, H. KOLÁŘOVÁ, B. STEFKOVA, R. PRUCEK, L. KVÍTEK, A. PANACEK
Revealing the mechanism of synergistic antibacterial effect of silver nanoparticles in combination with vancomycin against Enterococcus species by fluorescence microscopy visualization. Journal of materials chemistry. B. 2025, ISSN: 2050-750X, PMID: 40814802,  PDF.
DUMUT, D., M. HAJDÚCH, A. ZACHARIAS, Q. DUAN, I. FRYDRYCH, Z. ROŽÁNKOVÁ, M. POPPER, D. GARIC, R. PAUN, A. CENTORAME, J. SHAH, M. MISTRÍK, P. DŽUBÁK, J. DE SANCTIS, D. RADZIOCH
Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis. Frontiers in Immunology. 2025, 16, 1491450, ISSN: 1664-3224 , PMID: 40013140,  PDF.

Books & book chapters

BUCHTOVÁ, T., M. MISTRÍK
Quantitative immunofluorescence microscopy , 1.vyd., Olomouc, Palacky University, 2021, 14, 89-100, Dedication: LO1304, ISBN: 978-80-244-6049-9,
DRÁBEK, J., V. DAS, P. DŽUBÁK, J. SROVNAL, J. BOUCHAL, M. HAJDÚCH, K. KOBERNA, A. LIGASOVÁ, M. MISTRÍK, J. DE SANCTIS
Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Intellectual property

REMOVABLE CULTURE KIT FOR CELL CULTURES GROWN ON CULTURE DISHES - PUV 2020-38048 (Mistrík) SEPARATOR
  1. Utility Model: CZ 34546. Granted: 16.11.2020. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří

Status: Available

MOLECULAR COMPLEX ASSEMBLY PARTICLES COMRISING BIS-R1, R2-DITHIOCARBAMATE-METAL COMPLEX AND A LIGAND, METHOD OF PREPARATION AND USE THEREOF - EP 18199181.1 (Mistrík) DISULFIRAM II
  1. Published Application EP 18199181.1 under EP 3636285 (15.4.2020)
  2. Published Application PCT/EP2019/077222 under WO 2020/074514 (16.4.2020)
  3. Patent: AU 2019358428. Granted: 17.11.2022. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  4. Patent: CA 3,114,031. Granted: 12.3.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  5. Patent: IL 281616. Granted: 2.4.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  6. Patent: US 12,303,531. Granted: 20.5.2025. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  7. Patent: JP 7220932. Granted: 3.2.2023. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  8. Patent: BR 1120210061703. Granted: 18.2.2026. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  9. Patent: MX 418,133. Granted: 29.10.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  10. Patent: KR 10-2626651. Granted: 17.1.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián

Status: Available

BIOAVAILABLE DITHIOCARBAMATE-METAL COMPLEX NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF - EP 17193240.3 (Škrott) DISULFIRAM I
  1. Patent: EP 3459526. Granted: 24.2.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  2. Published Application: PCT/EP2018/076098 under WO 2019/063601 (4.4.2019)
  3. Patent: US 11,766,404. Granted: 26.9.2023. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  4. Patent: AU 2018340510. Granted: 5.8.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  5. Patent: IL 273652. Granted: 2.1.2024. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  6. Patent: CA 3,076,855. Granted: 26.4.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  7. Patent: KR 10-2456683. Granted: 14.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  8. Patent: JP 7149624. Granted: 29.9.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  9. Patent: MX 396,552. Granted: 17.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
  10. Patent:  BR 112020005823-8. Granted: 12.11.2024. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.

Status: Available

Doctoral mentorship

Škrott Zdeněk Ph.D.

The role of the ubiquitin-proteasome system in tumorigenesis and cancer treatment

Status: Graduated from 2014 to 2019.

Buchtová Tereza M.Sc.

Proteotoxic stress

Status: Graduated from 2018 to 2023.

Veselá Eva M.Sc.

Application of quantitative microscopy analysis of DNA damage for study of cell response to γ-irradiation and radiomimetic compounds in different genetic backrounds.

Status: Graduated from 2011 to 2017.

Master mentorship

Veselá Eva M.Sc.

Quantitative analysis of DNA damage markers and optimization of the methods for routine screening of potentially genotoxic compounds and factors

Status: Graduated from 2009 to 2011.

Votroubek Ondřej

Effect of CuET and DNA damage inductors on DNA replication in cancer cells

Status: Graduated from 2021 to 2024.

Bachelor mentorship

Veselá Eva M.Sc.

Identification and quantification of DNA damage in human cells

Status: Graduated from 2008 to 2009.

Open positions

1 Molecular and cellular biology
Project: DNA damage signaling in the cellular response to stress
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
2 Molecular and Translational Medicine
Project: Cellular stress in health and disease
Supervisors: Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available: 3
Intended for: Doctoral training
Project: Identification of cellular stress pathways essential for cancer cell survival
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position

WHERE TO FIND US

Hněvotínská 1333/5
779 00 Olomouc
Czech Republic

+420 585632111
+420 585632180
recepce.umtm@upol.cz
info@imtm.cz

GPS: 49° 35´ 10.1869512" N, 17° 14´ 6.292305" E

ABOUT IMTM

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