Slavkovský Rastislav Ph.D.

Academic Title: Ing.
Phone: +420 585632186

I am a research scientist passionate for molecular and cellular biology, DNA microarray, masive parallel sequencing and gene-expresion analysis. I always enjoy datamining of biologicaly relevant data and the comparison of data with already known information. I was involved in different studies such as wound healing characterization, experimental diabetes mellitus, effect of potentially active compounds or radiation on cells in vitro. I was responsible for a developement of a small laboratory for studing microbial biofilm in vitro. With my collegues, we are working on the developement of methods for predicive diagnostics of colorectal cancer, cardiomyopathy related genes and methylome profiling. Currently we are also studying how the somatic mutations in blood cells that are appearing during aging are connected to different vascular pathologic processeses. 

Publications (Impact Factor Journals)

  • [7]
    JAWOREK, H., K. KUBÁŇOVÁ, V. KOUDELÁKOVÁ, R. SLAVKOVSKÝ, J. DRÁBEK a M. HAJDÚCH. Pitfalls of commercially available HPV tests in HPV68a detection. PLOS One. 2019, 14(8), e0220373. ISSN 1932-6203. IF: 2.776. PMID: 31381580
  • [6]
    JAWOREK, H., V. KOUDELÁKOVÁ, R. SLAVKOVSKÝ, J. DRÁBEK a M. HAJDÚCH. The absence of high-risk human papillomavirus in Czech non-small cell lung cancer cases. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2019, -, -. ISSN 1213-8118. IF: 1.087. PMID: 30631209
  • [5]
    KLEIN, P., M. SOJKA, J. KUČERA, J. MATONOHOVA, V. PAVLIK, J. NEMEC, G. KUBICKOVA, R. SLAVKOVSKÝ, K. SZUSZKIEWICZ, P. DANEK, M. ROZKOT a V. VELEBNY. A porcine model of skin wound infected with a polybacterial biofilm. Biofouling. 2018, 34(2), 226-236. ISSN 0892-7014. IF: 3.080. PMID: 29405092
  • [4]
    MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE a J. LOIZOU. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nature Communications. 2017, 8(1), 1238. ISSN 2041-1723. IF: 12.124. PMID: 29089570
  • [3]
    PLEVOVA, P., M. PAPRSKÁŘOVÁ, P. TVRDA, P. TURSKA, R. SLAVKOVSKÝ a E. MRAZKOVA. STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic. Otology & Neurotology. 2017, 38(10), e393-e400. ISSN 1531-7129. IF: 2.024. PMID: 28984810
  • [2]
    KLASKOVA, E., J. DRÁBEK, M. HOBZOVA, V. SMOLKA, M. SEDA, J. HYJÁNEK, R. SLAVKOVSKÝ, J. STRÁNSKÁ a M. PROCHAZKA. Significant phenotype variability of congenital central hypoventilation syndrome in a family with polyalanine expansion mutation of the PHOX2B gene. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 495-498. ISSN 1213-8118 . IF: 0.894. PMID: 27485184
  • [1]
    STRÁNSKÁ, J., S. JANČÍK, R. SLAVKOVSKÝ, V. HOLINKOVÁ, M. RABČANOVÁ, P. VOJTA, M. HAJDÚCH a J. DRÁBEK. Whole genome amplification induced bias in the detection of KRAS-mutated cell populations during colorectal carcinoma tissue testing. Electrophoresis. 2015, 36(6), 937-40. ISSN 0173-0835. IF: 2.482. PMID: 25655305
  • Publications (Other Reviewed Journals)

  • [1]
    ONDRYÁŠOVÁ, H., V. KOUDELÁKOVÁ, J. DRÁBEK, P. VANEK, R. SLAVKOVSKÝ a M. HAJDÚCH. Utilization of self-sampling kits for HPV testing in cervical cancer screening - pilot study. Česká gynekologie. 2015, 80(6), 436-443. ISSN 1210-7832.

  • Doctoral students mentor:

    [1] Barbora Koblihová, Genetic biomarkers of tumors and aging,
    Ph.D. specialization: , status: Ongoing, from: 2019

    Master students mentor:

    [7] Lucia Csergeova, Genotyping of tumor somatic biomarkers using multi-parallel sequencing technologies with molecular barcodes features,
    status: Ongoing, from: 2019
    [6] Barbora Koblihová, Optimization of somatic mutation diagnostics in selected tumors with help of massive parallel sequencing,
    status: Graduated, from: 2017 to 2019
    [5] Gabriela Fryčová, Methylome profiling in cancer cells for identification of bevacizumab response biomarkers,
    status: Graduated, from: 2016 to 2018
    [4] Natália Podhorská, Epigenetic changes detection in cancer cells,
    status: Graduated, from: 2015 to 2017
    [3] Lenka Vysloužilová, Significance assessment of gene variants identified by next-generation sequencing associated with inherited cardiomyopathies,
    status: Ongoing, from: 2017
    [2] Lucie Kotková, Optimization of library preparation for NGS,
    status: Graduated, from: 2015 to 2017
    [1] Veronika Věnsková, Diagnostics of mutations in RAS family oncogenes in tumors using next-generation sequencing,
    status: Graduated, from: 2014 to 2016

    Bachelor students mentor:

    [3] Lucia Csergeova, Genotyping of tumor biomarkers using novel multi-parallel sequencing technologies with an emphasis on ultra sesnsitive typing of circulating tumor DNA,
    status: Graduated, from: 2017 to 2019
    [2] Gabriela Fryčová, Methylome profile changes in cancer cells associated with drug resistance,
    status: Graduated, from: 2013 to 2016
    [1] Lenka Vysloužilová, High-throughput sequencing and its use for identifying inherited causes of cardiomyopathies,
    status: Graduated, from: 2013 to 2016