News

Friday, February 12, 2021

Scientists burned the Blesk News logo into a human cell to show the breakthrough method

Tuesday, February 2, 2021

Scientists have unveiled a breakthrough method in the research of the proteotoxic stress of cells that leads to neurodegenerative diseases and ca...

Wednesday, January 27, 2021

Czech Philharmonic's CEO David Mareček and his staff visit our Institute in order to discuss the gargling tests.

Thursday, January 21, 2021

New variants of the virus coming from different parts of the world.

Events

Featured publications

VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E.

USSI. Bridging the translational innovation gap through good biomarker practice. Nature Reviews. Drug Discovery. 2017, 16(9), 587-588. ISSN 1474-1776 . IF: 57.000. PMID: 28450744

GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E.

USSI. Putting translational science on to a global stage. Nature Reviews Drug Discovery. 2016, 15, 217-219. ISSN 1474-1776. IF: 57.000. PMID: 27032820

MAYA-MENDOZA, A., P. MOUDRÝ, J. MERCHUT-MAYA, M. LEE, R. STRAUSS a J. BÁRTEK.

High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018, 559(7713), 279-284. ISSN 0028-0836. IF: 41.577. PMID: 29950726

ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715

XU, G., J. CHAPMAN, I. BRANDSMA, J. YUAN, M. MISTRÍK, P. BOUWMAN, J. BARTKOVA, E. GOGOLA, D. WARMERDAM, M. BAZARAS, J. JASPERS, K. WATANABE, M. PIETERSE, K. KERSBERGEN, W. SOL, P. CELIE, P. SCHOUTEN, B. VAN DEN BROEK, A. SALMAN, M. NIEUWLAND, I. DE RINK, J. DE RONDE, K. JALINK, S. BOULTON, J. CHEN, D. VAN GENT, J. BÁRTEK, J. JONKERS, P. BORST a S. ROTTENBERG.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015, 521(7553), 541-544. ISSN 0028-0836. IF: 38.138. PMID: 25799992

DIETLEIN, F., B. KALB, M. JOKIC, E. NOLL, A. STRONG, L. THARUN, L. OZRETIC, H. KUNSTLINGER, K. KAMBARTEL, W. RANDERATH, C. JUNGST, A. SCHMITT, A. TORGOVNICK, A. RICHTERS, D. RAUH, F. SIEDEK, T. PERSIGEHL, C. MAUCH, J. BARTKOVA, A. BRADLEY, M. SPRICK, A. TRUMPP, R. RAD, D. SAUR, J. BÁRTEK, J. WOLF, R. BUTTNER, R. THOMAS a H. REINHARDT.

A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer. Cell. 2015, 162(1), 146-159. ISSN 0092-8674. IF: 28.710. PMID: 26140595

ALL PUBLICATIONS

Technology & services

Featured research projects

Research infrastructures