Institute of Molecular and Translational Medicine

OL4PERMED: Abstract Submission is NOW OPEN!

OL4PERMED Olomouc for Personalized Medicine conference has opened the abstract submission. The OL4PERMED meeting program will cover latest topics of pathology, molecular pathology, predictive oncology, and histology as well as COVID-19 section

IMTM Reactor 2021

This year's IMTM Reactor will be held on October 6th – 8th at Skalský Dvůr hotel. It will be focused to recent develompent in IMTM and related laboratories and should serve to connecting and strenghtening of inter-laboratory collaboration within the Institute.

New topics of bachelor's theses opened!

IMTM LF UP in the cooperation with CGB laboratories Ostrava open new bachelor thesis for the academic year 2021/2022. Great opportunity of the theses elaboration and holiday practice in CGB laboratories Ostrava!

REVIEW: Coronavirus infection: An immunologists' perspective

Coronavirus infections are frequent viral infections in several species. As soon as the severe acute respiratory syndrome (SARS) appeared in the early 2000s, most of the research focused on pulmonary disease. However, disorders in immune response and organ dysfunctions have been documented. Elderly individuals with comorbidities exhibit worse outcomes in all the coronavirus that cause SARS.

A breakthrough method in the research of the proteotoxic stress of cells

Scientists have unveiled a breakthrough method in the research of the proteotoxic stress of cells that leads to neurodegenerative diseases and cancer.

IMTM's director Marián Hajdúch is a member of The Research, Development and Innovation Council

We are pleased to inform you that the director of ÚMTM Marián Hajdúch has become a member of The Research, Development and Innovation Council (R&D&I Council). R&D&I Council is a professional and consultancy body of the Government of the Czech Republic in the field of research, experimental development and innovation.

IMTM WILL BE PART OF THE OF THE CZECH ADVANCED TECHNOLOGY AND RESEARCH INSTITUTE

The Palacký University Academical Senate has approved the Statute of the Czech Advanced Technology and Research Institute of the Palacky University (CATRIN), a new university institute into which university research centers will be integrated.

IMTM DECLARES WAR AGAINST COVID - 19

We confirm that the Laboratory of Experimental Medicine of the Institute of Molecular and Translational Medicine is in the final phase of implementation of high-throughput testing.

MOLECULAR BASIS OF DISEASES AND MOLECULAR TARGET

Research program aims at identification and description of metabolic pathways, signaling pathways, genetic and epigenetic changes causing human diseases, particularly focusing cancer, inflammatory and infectious diseases.

News

New research methods for an early detection of lung cancer

Monday, September 20, 2021

Clinical study supported by Cancer Research Foundation CR is about to lunch.

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Noc vědců 2021 na ÚMTM [CZ]

Tuesday, September 14, 2021

Zajímá vás, jak probíhá testování na Covid-19 v jedné z největších laboratoří v České republice?

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OL4PERMED: Abstract Submission is NOW OPEN!

Tuesday, September 7, 2021

OL4PERMED Olomouc for Personalized Medicine conference is an interdisciplinary platform to exchange and disseminate knowledge.

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REACTOR 2021

Monday, August 23, 2021

IMTM Reactor will be held on October 6th – 8th at Skalský Dvůr hotel

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Tweets by IMTM_Olomouc

Featured publications

VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E.

USSI. Bridging the translational innovation gap through good biomarker practice. Nature Reviews. Drug Discovery. 2017, 16(9), 587-588. ISSN 1474-1776 . IF: 57.000. PMID: 28450744

GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E.

USSI. Putting translational science on to a global stage. Nature Reviews Drug Discovery. 2016, 15, 217-219. ISSN 1474-1776. IF: 57.000. PMID: 27032820

MAYA-MENDOZA, A., P. MOUDRÝ, J. MERCHUT-MAYA, M. LEE, R. STRAUSS a J. BÁRTEK.

High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018, 559(7713), 279-284. ISSN 0028-0836. IF: 41.577. PMID: 29950726

ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715

XU, G., J. CHAPMAN, I. BRANDSMA, J. YUAN, M. MISTRÍK, P. BOUWMAN, J. BARTKOVA, E. GOGOLA, D. WARMERDAM, M. BAZARAS, J. JASPERS, K. WATANABE, M. PIETERSE, K. KERSBERGEN, W. SOL, P. CELIE, P. SCHOUTEN, B. VAN DEN BROEK, A. SALMAN, M. NIEUWLAND, I. DE RINK, J. DE RONDE, K. JALINK, S. BOULTON, J. CHEN, D. VAN GENT, J. BÁRTEK, J. JONKERS, P. BORST a S. ROTTENBERG.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015, 521(7553), 541-544. ISSN 0028-0836. IF: 38.138. PMID: 25799992

DIETLEIN, F., B. KALB, M. JOKIC, E. NOLL, A. STRONG, L. THARUN, L. OZRETIC, H. KUNSTLINGER, K. KAMBARTEL, W. RANDERATH, C. JUNGST, A. SCHMITT, A. TORGOVNICK, A. RICHTERS, D. RAUH, F. SIEDEK, T. PERSIGEHL, C. MAUCH, J. BARTKOVA, A. BRADLEY, M. SPRICK, A. TRUMPP, R. RAD, D. SAUR, J. BÁRTEK, J. WOLF, R. BUTTNER, R. THOMAS a H. REINHARDT.

A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer. Cell. 2015, 162(1), 146-159. ISSN 0092-8674. IF: 28.710. PMID: 26140595

ALL PUBLICATIONS

OL4PERMED: Abstract Submission is NOW OPEN!

IMTM Reactor 2021

New topics of bachelor's theses opened!

REVIEW: Coronavirus infection: An immunologists' perspective

A breakthrough method in the research of the proteotoxic stress of cells

IMTM's director Marián Hajdúch is a member of The Research, Development and Innovation Council

IMTM WILL BE PART OF THE OF THE CZECH ADVANCED TECHNOLOGY AND RESEARCH INSTITUTE

IMTM DECLARES WAR AGAINST COVID - 19

MOLECULAR BASIS OF DISEASES AND MOLECULAR TARGET

News

New research methods for an early detection of lung cancer

Noc vědců 2021 na ÚMTM [CZ]

OL4PERMED: Abstract Submission is NOW OPEN!

REACTOR 2021

Twitter Follow us

Events

OL4PERMED November 25 – 27, 2021

Featured publications

VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E.

GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E.

MAYA-MENDOZA, A., P. MOUDRÝ, J. MERCHUT-MAYA, M. LEE, R. STRAUSS a J. BÁRTEK.

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