Contakt

Agrawal Khushboo PhD

E-mail: khushboo.agrawal@upol.cz
Phone: +420 585632339, +420 608706055
Curriculum Vitae: download here

I pursue the goal of learning and contributing my expertise to the field of cancer drug discovery, and look forward to coordinate and conduct research on the causes of human cancer, to unveil the various prospects of application in my field of interest. My research interest exquisitely lies in cancer epigenetics, mainly involving the study of chemotherapeutic resistance and investigation of novel biomarkers, hence furthering clinical development.

Publications (Impact Factor Journals)

  • [5]
    AGRAWAL, K., V. DAS, N. TÁBORSKÁ, J. GURSKÝ, P. DŽUBÁK a M. HAJDÚCH. Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs. Stem Cells International. 2018, 2018, 6013728. ISSN 1687-966X. IF: 3.989. PMID: 30158986
  • [4]
    AGRAWAL, K., V. DAS, P. VYAS a M. HAJDÚCH. Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic. Pharmacology & Therapeutics. 2018, 188, 45-79. ISSN 0163-7258. IF: 11.127. PMID: 29454856
  • [3]
    ANNADURAI, N., K. AGRAWAL, P. DŽUBÁK, M. HAJDÚCH a V. DAS. Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease. Cellular and Molecular Life Sciences. 2017, 74(22), 4159-4169. ISSN 1420-682X. IF: 5.788. PMID: 28634681
  • [2]
    AGRAWAL, K., V. DAS, M. OTMAR, M. KRECMEROVA, P. DŽUBÁK a M. HAJDÚCH. Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models. Cytometry A. 2016, -, -. ISSN 1552-4922 . IF: 3.222. PMID: 27911980
  • [1]
    HRUBY, M., K. AGRAWAL, O. POLICIANOVA, J. BRUS, J. SKOPAL, P. SVEC, M. OTMAR, P. DŽUBÁK, P. STEPANEK a M. HAJDÚCH. Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(2), 222-230. ISSN 1213-8118 . IF: 0.894. PMID: 27003313

  • Patents, Utility models & other IP's :

    [1] METHOD OF PREDICTING THE TUMOR RESPONSE TO DNA METHYLATION INHIBITORS AND ALTERNATIVE THERAPEUTIC REGIMENS FOR OVERCOMING RESISTANCE, EP 14161897.5
    1. Patent appl. EP 14161897.5 (ASH1L), Patent: EP 2924125, Granted: 17. 6. 2017, Ownership: Palacky University Olomouc, Inventors: Agrawal Khushboo, Frydrych Ivo, Džubák PetrHajdúch Marián
    2. Published Application EP 16158309.1 (JQ1) [divisional] under EP 3042650 (13. 7. 2016)
    3. Published Application PCT/CZ2015/000029 under WO 2015/144102 (1. 10. 2015)
    4. Patent appl. EP 15717786.6 (BRD4), Patent: EP 3122902, Granted: 16. 5. 2018, Ownership: Palacký University, Olomouc, Inventors: Agrawal KhushbooFrydrych IvoDžubák PetrHajdúch Marián
    5. Published Application US 15/128,390 under US 20180251847 (6.9.2018)
    6. Patent appl. JP 2016-559355 (BRD4), Patent: JP 6463372, Granted: 11. 1. 2019, Ownership: Palacký University, Olomouc, Inventors: Agrawal KhushbooFrydrych IvoDžubák PetrHajdúch Marián

    ​Status: Available