Ligasová Anna Ph.D.

EDUCATION

2002 – 2009     Title PhD, 1st. Faculty of Medicine, Charles University in Prague, Thesis: “DNA Replication and Chromatin: from 3D to Function”.

2009                   Title RNDr., Faculty of Science, Charles University in Prague

1997 – 2002     Title MSc., Faculty of Natural Sciences, Comenius University in Bratislava; Specialization: Cytology; Diploma Thesis: “The Effect of Stimuli and Beta-                               adrenergic Blockers on the Serotonin Release from the Human Blood Platelets in vitro”.

PUBLICATIONS

1. Ligasová, A., et al. (2017) PLoS One 12(4): e0175880
2. Ligasová, A., et al. (2017) PLoS One 12(3): e0174893
3. Ligasová, A., et al. (2016) Open Biol, 6:150172
4. Ligasová, A., Koberna, K. (2015) Methods Mol. Biol., 1351:81-92, M. McKenzie ed.
5. Ligasová, A., et al. (2015) PLoS One 10(7): e0132393
6. Ligasová, A., et al. (2015) PLoS One, 10(2): e0117459
7. Cmarko, D., et al. (2014) Methods Mol. Biol., 1117:343-66, John Kuo ed.
8. Ligasová, A., et al. (2013) PLoS One, 8(6):e66864
9. Ligasová, A., et al. (2012) PLoS One, 7(12):e52584
10. Liboska, R., et al. (2012) PLoS One, 7(12):e51679
11. Ligasová, A., et al. (2011) Parasit. Vectors, 4:162
12. Ligasová, A., Koberna, K. (2011) DNA replication-Current Advances, Intech, H. Seligmann ed.
13. Ligasová, A., Koberna K. (2010) Nucleic Acids Res., 38(16):e167
14. Ligasová, A., et al. (2009) J. Struct. Biol., 165(3):204-213
15. Cvačková, Z., et al. (2008) Chromosoma, 117(5):487-497
16. Kalmárová, M., et al. (2007) J. Struct. Biol., 160(1):49-56
17. Koberna, K., et al. (2005) J. Cell Biochem., 94(1):126-138

PATENTS

• No. 307016: Method of stabilisation of antibodies recognizing  5-bromo-2´-deoxyuridine and/or 5-chloro-2´-deoxyuridine and/or 5-iodo-2´-deoxyuridine at sites of incorporation of these nucleosides into DNA after the acton of monovalent copper ions and/or exonuclease III
• No. 306187: Apparatus for magnetic separation of ferromagnetic particles, set for magnetic separation of particles, separation process of magnetic particles from a solution and use of the apparatus or set for magnetic separation of particles
• No. 303230: Method for the revelation of specific pyrimidine nucleosides in the structure of the double-stranded DNA for the reaction with antibodies that react with these nucleosides
• No. 303251: Method for the labeling of double-stranded DNA molecules
• No. 303252: Method for the elimination of antigen attribute of 5-ethynyl-2'-deoxyuridine and 5-ethynyluridine in the detection of nucleic acids
• No. 302613: Method for the detection of RNA molecules polyadenylated at the 3´ end and RNA molecules containing inner parts composed of several adenines by means of 5-bromo-2´-deoxyuridine, 5-iodo-2´-deoxyuridine and 5-chloro-2´-deoxyuridine in the triphosphate form in the permeabilised cells and tissues and on the sections of cells and tissues.

UTILITY MODELS

No. 28964: Kit for accessing specific pyrimidine nucleosides in the structure of two-chain DNA for reaction with antibodies that react with these nucleosides