Džubák Petr M.D., Ph.D.

Journals

IVASECHKO, I., A. LOZYNSKYI, J. SENKIV, P. ROSZCZENKO, Y. KOZAK, N. FINIUK, O. KLYUCHIVSKA, N. KASHCHAK, N. MANKO, Z. MASLYAK, D. LESYK, A. KARKHUT, S. POLOKVOVYCH, R. CZARNOMYSY, O. SZEWCZYK, A. KOZYTSKIY, O. KARPENKO, D. KHYLUK, A. GZELLA, K. BIELAWSKI, A. BIELAWSKA, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH, R. STOIKA, R. LESYK
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone). European Journal of Medicinal Chemistry. 2023, 252, 115304, ISSN: 0223-5234, PMID: 37001390,  PDF.
OŽDIAN, T., J. VODICKA, J. DOSTÁL, D. HOLUB, J. VÁCLAVKOVÁ, M. JESETA, B. HAMERNÍKOVÁ, P. KOUŘILOVÁ, O. MALCHAR, V. DVORAK, P. HEJTMANEK, K. SOBKOVA, P. VENTRUBA, R. PILKA, P. DŽUBÁK, M. HAJDÚCH
Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders. International Journal of Molecular Sciences. 2023, 24(2), 1038, ISSN: 1422-0067, PMID: 36674559,  PDF.
JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR, P. DŽUBÁK
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN: 0045-2068, PMID: 36592487,  PDF.

Intellectual property

BENZOISOTHIAZOLE-1, 1-DIOXIDE-3-HYDRAZONES AND THEIR USE IN ANTICANCER THERAPY (Kaplánek)
  1. Patent: CZ 306554. Granted: 25.1 2017. Ownership: Institute of Chemical Technology Prague; Palacký University Olomouc; Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, BŘÍZA Tomáš, HAVLÍK Martin, RAK Jakub, KEJÍK Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír

​Status: Terminated

DIOXOCYCLOBUTENYL HYDRAZONES AND THEIR ANTICANCER ACTIVITY (Kaplánek)
  1. Patent: CZ 305626. Granted: 2.12.2015. Ownership: Institute of Chemical Technology Prague; Palacký University Olomouc; Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, BŘÍZA Tomáš, HAVLÍK Martin, RAK Jakub, KEJÍK Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír

​Status: Terminated

CAFFEINE-8-HYDRAZONES AS NOVEL CYTOSTATICS FOR THE TREATMENT OF ONCOLOGIC DISEASES (Kaplánek)
  1. Patent: CZ 305625. Granted: 2.12.2015. Ownership: Institute of Chemical Technology Prague, Palacký University Olomouc, Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, JAKUBEK Milan, HAVLÍK  Martin, RAK, BŘÍZA Tomáš, DŽUBÁK Petr, HAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír 

Status: Terminated 

Doctoral mentorship

Heffnerová Ema

Identification of molecular targets and mechanisms of resistance in anticancer drugs by cell biology methods and proteomics

Status: Ongoing from 2024.
Bartáková Anna

Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease

Status: Ongoing from 2024.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study