Contakt

Frydrych Ivo Ph.D.

Phone: +420 585 632 145
Groups: ÚMTM, LEM, Staff, Postdoctoral Fellow

Postdoctoral training

Status: Ongoing.

About me

My research interests focus on development and validation of cellular gen reporters for high-throughput screening (HTS) of biologically active compounds. I´m working on a development of luminiscent technologies for mapping of cell signalling pathways activation/inhibition  as a powerful tool for assessing the biological impact of small molecule compounds. The another goal is development of cellular fluorescent  models for monitoring cell death hallmarks. My current research focuses on the investigation of pyrimidine derivatives as potential inhibitors of RAGE receptor, which is implicated in the regulation of diverse pathological conditions such as cancer, neurodegenerative diseases, diabetes or inflammation.
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