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Academic title: Mgr.
Phone: 585632048
Groups: BACHELOR STUDENT, DOCTORAL STUDENT, IMTM, LEM, MASTER STUDENT, STAFF

Doctoral training

Drug resistance mechanisms in cancer

Specialization: Molecular and Translational Medicine
Status: Ongoing from 2020.

Master training

Development and characterization of resistant cell lines to purine and pyrimidine cytotoxic drugs

Status: Graduated from 2018 to 2020.

Bachelor training

Spectroscopic characteristics used drugs and their use in the identification of molecular targets

Supervisor: Stanková Jarmila
Status: Graduated from 2016 to 2018.

About me

Ph.D. student specializing in molecular and cell biology, with a primary research focus on identifying and characterizing modulators of G protein-coupled receptors (GPCRs), particularly adenosine receptor agonists and antagonists. Possesses practical experience in cancer cell biology, molecular biology techniques, and high-throughput screening methodologies.

Journals

SINKEVICIUTE, U., K. BURGETOVÁ JEČMEŇOVÁ, S. GURSKÁ, L. POSTOVA SLAVETINSKA, V. BARAN, P. POLISHCHUK, P. DŽUBÁK, M. HOCEK, M. HAJDÚCH, M. TICHÝ
Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases. ChemMedChem. 2026, 21(16), e70419, ISSN: 1860-7179, PMID: 42596056,  PDF.
JURÁŠEK, M., E. DRABEROVA, J. ŘEHULKA, S. GURSKÁ, A. IVANOVA (NIKONENKO), P. POLISHCHUK, K. BURGETOVÁ JEČMEŇOVÁ, J. FAHNRICH, A. MARESOVA, J. TAUCHEN, A. REYES ROMERO, A. DÖMLING, M. HAJDÚCH, P. DRAŠAR, P. DRABER, P. DŽUBÁK
Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin. ACS pharmacology & translational science. 2025, 8(7), 1965-1985, ISSN: 2575-9108, PMID: 40672674,  PDF.
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Journal of enzyme inhibition and medicinal chemistry. 2024, 39(1), 2367139, ISSN: 1475-6366 , PMID: 38904149,  PDF.

Master mentorship

Fialová Kateřina

Optimization of High-Throughput Screening for Potential Modulators of Purinergic Receptors

Status: Graduated from 2024 to 2026.

Bachelor mentorship

Fialová Kateřina

siRNA knock-down of A3 adenosine receptor

Status: Graduated from 2022 to 2024.