Urban Milan Ph.D.

Journals

PORUBSKÝ, M., J. HODOŇ, J. STANKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN, J. HLAVÁČ
Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/cRGD targeted photodynamic therapy. Journal of photochemistry and photobiology. 2024, 113010, ISSN: 1011-1344, PMID: 39141981,
KAZAKOVA, A., I. FRYDRYCH, N. JAKUBCOVÁ, J. POKORNÝ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.
BORKOVÁ, L., I. FRYDRYCH, B. VRÁNOVÁ, N. JAKUBCOVÁ, B. LIŠKOVÁ, P. DŽUBÁK, P. PAVLIŠ, M. HAJDÚCH, M. URBAN
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes. European Journal of Medicinal Chemistry. 2022, 244, 114850, ISSN: 0223-5234, PMID: 36283179,

Books & book chapters

DŽUBÁK, P., M. URBAN, M. HAJDÚCH
Vývoj nových léčiv, 1. vyd, Praha, Galén, 2015, 11, 469-472, ISBN: 978-80-7492-121-6,
URBAN, M., M. KVASNICA, N. DICKINSON, J. ŠAREK
Biologically Active Triterpenoids Usable As Prodrugs, 1. vyd, New York, USA, Nova Science Publishers, 2015, 2, 25-50, Dedication: CZ.1.05/2.1.00/01.0030, ISBN: 978-1-63463-656-8,
ŠAREK, J., M. KVASNICA, M. VLK, M. URBAN, P. DŽUBÁK, M. HAJDÚCH
The Potential of Triterpenoids in the Treatment of Melanoma, 1.vyd, Rijeka, InTech, 2011, 7, 125-158, Dedication: 305/09/1216, ISBN: 978-953-307-293-7,

Intellectual property

SONIC HEDGEHOG (Urban)
  1. Patent: CZ 309885. Granted: 30.11.2023. Ownership: Palacký University Olomouc. Inventors: URBAN Milan, FRYDRYCH Ivo, BORKOVÁ Lucie, VRÁNOVÁ Barbora, HAJDÚCH Marián. 

Status: Available

TERPENOID DERIVATIVES, PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN NEUROPROTECTION (Urban)
  1. Patent: CZ 309944. Inventors: URBAN Milan, GONZALEZ Gabriel, HODOŇ Jiří, STRNAD Miroslav. Ownership: Palacký University Olomouc.
  2. Published Application: PCT/CZ2021/050146 under WO 2022/117133 (9.6.2022). Inventors: URBAN Milan, GONZALEZ Gabriel, HODOŇ Jiří, STRNAD Miroslav. Ownership: Palacký University Olomouc.

 Status: Available 

Doctoral mentorship

Bachořík Jan

Preparation of semisynthetic triterpenes

Status: Ongoing from 2019.
Orság Šimon

Preparation of new heterocyclic derivatives of triterpene

Status: Ongoing from 2022 to 2022.
Jurčeka Ondřej

Modification of lupine triterpenes in position C-17

Status: Ongoing from 2022.

Master mentorship

Maršálková Natálie

Status: Ongoing.
Horka Vladimír

Conjugates of betulin prepared by cycloaddition reactions

Status: Graduated from 2018 to 2020.
Pisár Martin

Preparation of semisynthetic derivatives of betulinic acid with cytotoxic activity

Status: Graduated from 2017 to 2019.

Bachelor mentorship

Zamazal Viktor

Preparation of new triterpene derivatives based on sulfur

Status: Ongoing from 2022.
Jarošová Amálie

Preparation of new nitrogen-based triterpene derivatives

Status: Ongoing from 2022.
Oriešková Eliška

Preparation of new triterpene derivatives based on peptides

Status: Ongoing from 2022.

Open positions

Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training