Džubák Petr M.D., Ph.D.

Journals

FRYDRYCH, I., B. CHROMA, L. SLAVIKOVA, J. POKORNÝ, N. JAKUBCOVÁ, S. LUDHA, S. GURSKÁ, J. ŘEHULKA, B. LIŠKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel C-2 Aromatic Heterocycle-Substituted Triterpenoids Inhibit Hedgehog Signaling in GLI1 Overexpression Cancer Cells. ACS Omega. 2025, 10(10), 10617-10632, ISSN: 2470-1343, PMID: 40124057,  PDF.
RAMPEESA, N., R. GUNDLA, G. MUDASANI, S. TANGALLAPALLI, S. ANUGU, S. GURSKÁ, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, V. DAS
Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity. Bioorganic Chemistry. 2025, 157, 108316, ISSN: 0045-2068, PMID: 40037026,  PDF.
MUDSANI, G., N. RAMPEESA, S. ANUGU, P. MUDDASANI, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH
Design, synthesis, and biological evaluation of novel azaspirooxindolinone derivatives as potent inhibitors of ITK and BTK-dependent cancers. Bioorganic & Medicinal Chemistry. 2025, 121, 118116, ISSN: 0968-0896, PMID: 40015119,  PDF.

Books & book chapters

DŽUBÁK, P.
Detection and quantification of cellular antigens using flow cytometry, 1.vyd., Olomouc, Palacky University, 2021, 28, 209-214, Dedication: LO1304, ISBN: 978-80-244-6049-9,
DRÁBEK, J., V. DAS, P. DŽUBÁK, J. SROVNAL, J. BOUCHAL, M. HAJDÚCH, K. KOBERNA, A. LIGASOVÁ, M. MISTRÍK, J. DE SANCTIS
Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
DŽUBÁK, P.
Hmotnostní spektrometrie, 1. vyd, korigovaný dotisk, Olomouc, Univerzita Palackého v Olomouci, 2021, 2.2, 34-42, ISBN: 978-80-244-3951-8,

Intellectual property

PYRROLOQUINOLINES AND THEIR USE AS TUBULINE ASSEMBLY INHIBITORS (Soural)
  1. Published Application PCT/CZ2023/050038 under WO 2025/008012 (9.1.2025)
RNA ISOLATION KIT (Džubák)

Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, GURSKÁ Soňa, KOUDELÁKOVÁ Vladimíra, JAWOREK Hana.

Status: Available

MEDIUM FOR TRANSPORTING AND STORING VIRUSES (Hajdúch)

Utility Model: CZ 35138. Granted: 8.6.2021. Ownership: Palacký University Olomouc. Inventors: HAJDÚCH Marián, DŽUBÁK Petr, JAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.

Status: Available

Postdoctoral mentorship

Znojek Pawel Ph.D.

HCT/HCA assays development

Status: Ongoing from 2013 to 2015.

Doctoral mentorship

Ječmeňová Kateřina

Drug resistance mechanisms in cancer

Status: Ongoing from 2020.
Kotulová Jana Ph.D.

Identification of adenosine receptor modulators and their anticancer properties

Status: Graduated from 2014 to 2022.
Stanková Jarmila

Cytotoxic drugs molecular target identification by methods of cell biology and proteomics

Status: Graduated from 2016 to 2024.

Master mentorship

Ječmeňová Kateřina

Development and characterization of resistant cell lines to purine and pyrimidine cytotoxic drugs

Status: Graduated from 2018 to 2020.
Růžičková Eliška B.Sc.

Evaluation of biological activity of demethylation drugs

Status: Graduated from 2013 to 2014.
Pastorková Barbora B.Sc.

Identification of molecular targets of anticancer drugs by immuno-affinity purification

Status: Graduated from 2013 to 2014.

Bachelor mentorship

Lónová Kateřina

Development and basic characterization of the cell line resistant to the CDK inhibitors

Status: Graduated from 2015 to 2016.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study