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PhD Club: CDK4/6 PROTACs: Advancing Targeted Protein Degradation for Pediatric Neuroblastoma by Samantha Masineni

Monday, March 17, 2025

Wednesday March 19, 2025 / 9 AM / The seminary room 1.09

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Czech Annual Cancer Research Meeting 2025: Registration and abstract submission are open

Thursday, March 13, 2025

Join us for the Czech Annual Cancer Research Meeting, taking place on November 24–26, 2025, in Olomouc. The conference will focus on the latest advancements in cancer research, molecular pathology, and predictive oncology.

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Phd Club: Targeting p53-Y220C: a PROTAC-Based Strategy for Selective Degradation by Imma Capriello

Monday, March 10, 2025

Wednesday March 12, 2025 / 9 AM / The seminary room 1.09

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Dávid Lukáč defended his dissertation thesis on DNA Replication and Cancer

Friday, March 7, 2025

The defense took place on March 6, 2025 at 1:30 p.m. at the Faculty of Medicine and Dentistry Palacký University Olomouc

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PhD Club lecture: Enhancing Streptomycin: Structural Modifications for Improved Efficacy and Reduced Toxicity by Kaoud Salama

Monday, March 3, 2025

Wednesday March 5, 2025 / 9 AM / The seminary room 1.09

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News archive

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Chcete se zúčastnit klinické studie Screening plicního karcinomu?

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Featured publications

WANG, Z., S. SHAABANI, X. GAO, Y. NG, V. SAPOZHNIKOVA, P. MERTINS, J. KRONKE, A. DÖMLING

Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery. Nature Communications. 2023, 14(1), 8437, ISSN: 2041-1723, IF: 16.6, PMID: 38114468.

PATIL, P., Q. ZHENG, K. KURPIEWSKA, A. DÖMLING

The isocyanide SN2 reaction. Nature Communications. 2023, 14(1), 5807, ISSN: 2041-1723, IF: 16.6, PMID: 37726293.

SONG, J., K. SUNDAR, M. HORVÁTHOVÁ, R. GANGARAJU, K. INDRAK, R. CHRISTENSEN, S. GENZOR, C. LUNDBY, V. DIVOKÝ, T. GANZ, J. PRCHAL

Increased blood reactive oxygen species and hepcidin in obstructive sleep apnea precludes expected erythrocytosis. American Journal of Hematology. 2023, 98(8), 1265-1276, ISSN: 0361-8609 , IF: 12.8, PMID: 37350302.

CARNA, M., I. ONYANGO, S. KATINA, D. HOLUB, J. NOVOTNÝ, M. NEZVEDOVA, D. JHA, Z. NEDELSKA, V. LACOVICH, T. VYVERE, R. HOUBRECHTS, K. GARCIA-MANSFIELD, R. SHARMA, V. DAVID-DIRGO, M. VYHNALEK, K. TEXLOVA, H. CHAVES, N. BAKKAR, L. PERTIERRA, M. VINKLER, H. MARKOVA, J. LACZO, K. SHEARDOVA, M. HORTOVA-KOHOUTKOVA, J. FRIC, G. FORTE, P. KANOVSKY, S. BELASKOVA, J. DAMBORSKY, J. HORT, N. SEYFRIED, R. BOWSER, G. SEVLEVER, R. RISSMAN, R. SMITH, M. HAJDÚCH, P. PIRROTTE, Z. SPACIL, E. DAMMER, C. LIMBACK-STOKIN, G. STOKIN

Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2023, -, -, ISSN: 1552-5260, IF: 16.655, PMID: 36825691.

YANG, C., L. POSTOVA SLAVETINSKA, M. FLEUTI, B. KLEPETAROVA, M. TICHÝ, S. GURSKÁ, P. PAVLIŠ, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK

Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling. Journal of the American Chemical Society. 2022, 144(42), 19437-19446, ISSN: 0002-7863, IF: 16.383, PMID: 36245092.

KVAKOVA, K., M. ONDRA, J. SCHIMER, M. PETŘÍK, Z. NOVÝ, H. RAABOVA, M. HAJDÚCH, P. CIGLER

Visualization of Sentinel Lymph Nodes with Mannosylated Fluorescent Nanodiamonds. Advanced Functional Materials. 2022, 32(23), 2109960, ISSN: 1616-301X, IF: 18.808,

WOLRAB, D., R. JIRASKO, E. CIFKOVA, M. HORING, D. MEI, M. CHOCHOLOUSKOVA, O. PETERKA, J. IDOWIAK, T. HRNCIAROVA, L. KUCHAR, R. AHRENDS, R. BRUMAROVÁ, D. FRIEDECKÝ, G. VIVO-TRUYOLS, P. SKRHA, J. SKRHA, R. KUCERA, B. MELICHAR, G. LIEBISCH, R. BURKHARDT, M. WENK, A. CAZENAVE-GASSIOT, P. KARASEK, I. NOVOTNY, K. GREPLOVA, R. HRSTKA, M. HOLCAPEK

Lipidomic profiling of human serum enables detection of pancreatic cancer. Nature Communications. 2022, 13(1), 124, ISSN: 2041-1723, IF: 14.919, PMID: 35013261.

MOUDRÝ, P., K. CHROMÁ, S. BURSAC, S. VOLAREVIC, J. BÁRTEK

RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis. Cell Death and Differentiation. 2022, 29(3), 687-696, ISSN: 1350-9047, IF: 15.828, PMID: 34611297.

FANG, L., B. ZHU, Y. ZHAO, W. CHEN, Z. YANG, L. KERRIGAN, K. LANGEBACH, M. DE MARS, K. IDLER, H. JACOB, Y. ZHENG, Y. YU, E. JAEGER, G. SCHROTH, O. ABAAN, K. TALSANIA, J. LACK, T. SHEN, S. STANBOULY, B. TRAN, J. SHETTY, Y. KRIGA, D. MEERZAMAN, C. NGUYEN, V. PETITJEAN, M. SULTAN, M. CAM, M. MEHTA, T. HUNG, E. PETERS, R. KALAMEGHAM, S. SAHRAEIAN, M. MOHIYUDDI, T. GUO, L. YAO, L. SONG, H. LAM, J. DRÁBEK, P. VOJTA, R. MAESTRO, D. GASPAROTTO, S. KOKS, E. REIMANN, A. SCHERER, J. NORDLUND, U. LILJEDAHL, R. JENSEN, M. PIROOZNIA, Z. LI, C. XIAO, S. SHERRY, R. KUSKO, M. MOOS, E. DONALDSON, Z. TEZAK, B. NING, W. TONG, J. LI, P. DUERKEN-HUGHES, C. CATALANOTTI, S. MAHESHWARI, J. SHUGA, W. LIANG, J. KEATS, J. ADKINS, E. TASSONE, V. ZISMANN, T. MCDANIEL, J. TRENT, J. FOOX, D. BUTLER, C. MASON, H. HONG, C. WANG, W. XIAO, I. SOMATIC

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing. Nature Biotechnology. 2021, 39(9), 1151-60, ISSN: 1087-0156, IF: 54.908, PMID: 34504347.

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