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Moudrý Pavel Ph.D.
About me
I am studying molecular mechanisms that control DNA replication in normal and cancer cells. Specifically, I am interested in effects of clinically used PARP inhibitors on progression of replication forks. Understanding how PARP inhibitors regulate replication fork dynamics is critical to targeting and developing durable cancer therapies.
Positions for talented Master or PhD students interested in DNA replication and DNA repair are available. Feel free to contact me for detailed information.
Impact factor journals
Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments.
Life Science Alliance.
2022,
5(12),
e202201560,
ISSN: 2575-1077,
PMID: 36260751,
A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment.
Cell Death & Disease.
2022,
13(3),
203,
ISSN: 2041-4889,
PMID: 35246527,
RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis.
Cell Death and Differentiation.
2022,
29(3),
687-696,
ISSN: 1350-9047,
PMID: 34611297,
Doctoral mentorship
Master mentorship
Bachelor mentorship
Baťová Adéla
Cellular response to genotoxic and replication stress
Status:
Graduated from 2019 to 2021.
Open positions
| Project: | Cellular stress in health and disease |
|---|---|
| Supervisors: | Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D. |
| Available: | 3 |
| Intended for: | Doctoral training |