Urban Milan Ph.D.

Journals

PORUBSKÝ, M., J. HODOŇ, J. STANKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN, J. HLAVÁČ
Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/cRGD targeted photodynamic therapy. Journal of photochemistry and photobiology. 2024, 113010, ISSN: 1011-1344, PMID: 39141981,
KAZAKOVA, A., I. FRYDRYCH, N. JAKUBCOVÁ, J. POKORNÝ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.
BORKOVÁ, L., I. FRYDRYCH, B. VRÁNOVÁ, N. JAKUBCOVÁ, B. LIŠKOVÁ, P. DŽUBÁK, P. PAVLIŠ, M. HAJDÚCH, M. URBAN
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes. European Journal of Medicinal Chemistry. 2022, 244, 114850, ISSN: 0223-5234, PMID: 36283179,

Doctoral mentorship

Borková Lucie Ph.D.

Modification of triterpenes with the use of transition metal catalyzed reactions and nucleophilic substitution

Status: Graduated from 2014 to 2018.
Pokorný Jan Ph.D.

Modifications of double bonds in triterpenes with antitumor activity

Status: Graduated from 2015 to 2022.
Hodoň Jiří, Ph.D.

Cytotoxic active triterpenes and their mechanism of action

Status: Graduated from 2017 to 2024.

Master mentorship

Olejníková Denisa

Synthesis of new lupane derivatives modified at position 20 or 30

Status: Graduated from 2018 to 2020.
Šidová Veronika

Synthesis of new cytotoxic triterpenoid derivatives using click chemistry

Status: Graduated from 2013 to 2015.
Zoufalý Pavel

Exploraton of click reaction approach in triterpenoids containing propargyl substituent

Status: Graduated from 2014 to 2016.

Bachelor mentorship

Horka Vladimír

Conjugates of betulin prepared by cycloaddition reactions

Status: Graduated from 2016 to 2018.
Olejníková Denisa

Synthesis of new lupane derivatives modified at position 20 or 30

Status: Graduated from 2016 to 2018.
Orság Šimon

Preparation of new heterocyclic derivatives of triterpene

Status: Graduated from 2018 to 2020.

Open positions

Project: Natural compounds with anti tumor activity
Supervisors: Urban Milan Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training