Gurská Soňa Ph.D.

Journals

FRYDRYCH, I., B. CHROMA, L. SLAVIKOVA, J. POKORNÝ, N. JAKUBCOVÁ, S. LUDHA, S. GURSKÁ, J. ŘEHULKA, B. LIŠKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel C-2 Aromatic Heterocycle-Substituted Triterpenoids Inhibit Hedgehog Signaling in GLI1 Overexpression Cancer Cells. ACS Omega. 2025, 10(10), 10617-10632, ISSN: 2470-1343, PMID: 40124057,  PDF.
RAMPEESA, N., R. GUNDLA, G. MUDASANI, S. TANGALLAPALLI, S. ANUGU, S. GURSKÁ, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, V. DAS
Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity. Bioorganic Chemistry. 2025, 157, 108316, ISSN: 0045-2068, PMID: 40037026,  PDF.
MUDSANI, G., N. RAMPEESA, S. ANUGU, P. MUDDASANI, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH
Design, synthesis, and biological evaluation of novel azaspirooxindolinone derivatives as potent inhibitors of ITK and BTK-dependent cancers. Bioorganic & Medicinal Chemistry. 2025, 121, 118116, ISSN: 0968-0896, PMID: 40015119,  PDF.

Books & book chapters

GURSKÁ, S.
Analysis of cytotoxicity by tetrazolium salt reduction test , 1.vyd., Olomouc, Palacky University, 2021, 10, 67-72, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Intellectual property

RNA ISOLATION KIT (Džubák)

Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, GURSKÁ Soňa, KOUDELÁKOVÁ Vladimíra, JAWOREK Hana.

Status: Available

Master mentorship

Synek Vojtěch

Development of the assay for measurement of the CA activity and its implementation into HTS

Status: Graduated from 2018 to 2020.
Dostálová Kristýna

Cell-based assays for high-throughput screening in drug discovery

Status: Graduated from 2014 to 2016.
Voltemarová Tereza

Cytotoxicity profiling of new potentially bioactive compounds using high throughput screening (HTS)

Status: Graduated from 2019 to 2021.

Bachelor mentorship

Jamborová Petra

Establishment and characterization of anticancer drug resistant leukemic cell lines

Status: Graduated from 2023 to 2024.
Synek Vojtěch

Cytotoxicity tests for high-throughput drug discovery

Status: Graduated from 2014 to 2018.
Zabáková Dominika

Analysis of the cytotoxic effects of new chemical substances in HTS conditions

Status: Graduated from 2021 to 2021.