Džubák Petr M.D., Ph.D.

Journals

VELAVAPALLI, V., V. MADDIPATI, S. GURSKÁ, N. ANNADURAI, B. LIŠKOVÁ, N. KATARI, P. DŽUBÁK, M. HAJDÚCH, V. DAS, R. GUNDLA
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation. ACS Omega. 2024, 7(9), 8067-8081, ISSN: 2470-1343, PMID: 38405484,  PDF.
GUTIERREZ, J., H. RAMIREZ, E. FERNANDEZ-MOREIRA, M. ACOSTA, M. MIJARES, J. DE SANCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, L. LABRADOR-FAGÚNDEZ, B. STELLA, L. DIAZ-PEREZ, G. BENAIM, J. CHARRIS
Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives. Pharmaceuticals . 2023, 16(12), 1709, ISSN: 1424-8247, PMID: 38139835,  PDF.
KORABOINA, C., V. MADDIPATI, N. ANNADURAI, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, V. DAS, R. GUNDLA
Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors. ChemMedChem. 2023, ISSN: 1860-7179, PMID: 37916435,  PDF.

Books & book chapters

DRÁBEK, J., J. BERKOVCOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. KHOYLOU, V. KOUDELÁKOVÁ, J. SROVNAL, M. STAŇKOVÁ, R. TROJANEC
Detekce nádorových biomarkerů v molekulárně biologické laboratoři, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2012, 144 s, Dedication: MOLONKOL CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3002-7,
ŠAREK, J., M. KVASNICA, M. VLK, M. URBAN, P. DŽUBÁK, M. HAJDÚCH
The Potential of Triterpenoids in the Treatment of Melanoma, 1.vyd, Rijeka, InTech, 2011, 7, 125-158, Dedication: 305/09/1216, ISBN: 978-953-307-293-7,

Intellectual property

SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Patent: CZ 307334. Granted: 2.5.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  2. Published application PCT/CZ2017/050031 under WO 2018/024265 (8.2.2018)
  3. Patent: EP 3494122. Granted: 18.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  4. Patent: US 10,730,905. Granted: 4.8.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  5. Patent: JP 6685475. Granted: 2.4.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  6. Patent: CA 3.031.049. Granted: 7.7.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián

Status: Available

FLUORESCENT DERIVATIVE FOR NON-CATALYTIC LABELING OF NUCLEIC ACID AND PEPTIDE COMPONENTS (Jedináková)
  1. Utility Model: CZ 30136, Granted: 13.12.2016, Ownership: Palacký University Olomouc, Inventors: Jedináková Petra, Hlaváč Jan, Václavková Jana, Konečný Petr, Džubák Petr, Hajdúch Marián

Status: Terminated

SUBSTITUTED THIENOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
  2. Patent: EP 3478701. Granted: 10.8.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  3. Patent: US 10,414,788. Granted: 17.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  4. Patent: JP 6650074. Granted: 21.1.2020.  Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  5. Patent: CA 3.029.170. Granted: 16.2.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University, Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr

Status: Terminated

Doctoral mentorship

Holub Dušan Ph.D.

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS

Status: Graduated from 2009 to 2016.
Václavková Jana M.Sc.

Identification of mechanisms of action of molecules with anticancer effect

Status: Graduated from 2014 to 2021.
Hrubá Lenka RNDr., Ph.D.

Mechanism of multidrug resistance (MDR) in cancer cells

Status: Graduated from 2015 to 2023.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study