Řehulka Jiří Ph.D.

Phone: +420 585632069

Groups: DOCTORAL STUDENT, IMTM, LEM, STAFF

Assistant professor at the Institute of Molecular and Translational Medicine. He is involved in drug screening, confocal microscopy and image analysis. His research interests are microtubule targeting agents and mechanisms of resistance to antineoplastic chemotherapy drugs.

ŘEHULKA, J., M. JURÁŠEK, P. DRABER, A. IVANOVA (NIKONENKO), S. GURSKÁ, K. BURGETOVÁ JEČMEŇOVÁ, O. MOKSHYNA, M. HAJDÚCH, P. POLISHCHUK, P. DRAŠAR, P. DŽUBÁK

Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Journal of enzyme inhibition and medicinal chemistry. 2024, 39(1), 2367139, ISSN: 1475-6366 , PMID: 38904149, PDF.

JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR, P. DŽUBÁK

Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN: 0045-2068, PMID: 36592487, PDF.

ŘEHULKA, J., I. SUBTELNA, A. KRYSHCHYSHYN-DYLEVYCH, A. CHERNIIENKO, A. IVANOVA, M. MATVEIEVA, P. POLISHCHUK, S. GURSKÁ, M. HAJDÚCH, O. ZAGRIJTCHUK, P. DŽUBÁK, R. LESYK

Anticancer 5-arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones as tubulin inhibitors. Archiv der Pharmazie. 2022, 355(12), e2200419, ISSN: 0365-6233, PMID: 36109178,

Řehulka Jiří Ph.D.

About me

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