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Phone: +420 585 632 243
Groups: IMTM, LEM, STAFF

About me

Viswanath Das is a Principal Investigator and Group Leader at the Institute of Molecular and Translational Medicine, Palacký University Olomouc. His research focuses on the aggregation, prion-like seeding, and propagation of disease-associated proteins, including tau, α-synuclein, and amyloid, and on developing therapeutic strategies to inhibit these processes. He leads projects supported by the Czech Science Foundation and the Czech Ministry of Health. He has published more than 40 peer-reviewed articles and supervises postdoctoral, doctoral, and master’s researchers.

Journals

DEVIATOV, A., I. KOZLOV, V. DAS
Differentiation of SH-SY5Y Cells into Cortical Neuron-like Cells for Tauopathy Modeling and Seeding Assays. Molecular Neurobiology. 2025, ISSN: 0893-7648, PMID: 40467940,  PDF.
RAMPEESA, N., R. GUNDLA, G. MUDASANI, S. TANGALLAPALLI, S. ANUGU, S. GURSKÁ, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, V. DAS
Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity. Bioorganic Chemistry. 2025, 157, 108316, ISSN: 0045-2068, PMID: 40037026,  PDF.
DAS, V., J. MILLER, C. ALLADI, N. ANNADURAI, J. DE SANCTIS, L. HRUBÁ, M. HAJDÚCH
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies. Medicinal Research Reviews. 2024, 44(5), 2078-2111, ISSN: 0198-6325, PMID: 38530106,  PDF.

Master mentorship

Paciorková Ema

Biochemical and Cellular Analysis of Amyloid Staining Agents in Models of Tauopathies and Synucleopathies

Status: Graduated from 2023 to 2025.

Maxwell Victor Ezekiel

Development and validation of a wild-type alpha-synuclein RT-QuiC assay for sensitive detection of pathogenic alpha-synuclein seeds

Status: Ongoing from 2026.

Open positions

1 Chemical biology and experimental therapeutics
Project: The role of tumor hypoxia in the emergence of acquired resistance to drugs aimed at microtubules
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
8 Molecular and Translational Medicine
Project: Role of axonal transport and pathology in neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Systems approaches to understanding aging and neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Mitochondrial and microglial dysfunction in tauopathies: effects of pathogenic TAU strains
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Investigating Effects of Aggregates of Intrinsically Disordered Proteins on Microglia: Implication for Neurodegenerative Diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Generation of 3D human neuronal cultures: application to modeling CNS diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Efficacy of Bruton Tyrosine Kinase Inhibitors Against Neuroinflammation in Neurodegenerative Diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -