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Phone: +420 585 632 234
Groups: IMTM, LIG, STAFF, SUPERVISOR

About me

Head of the DNA replication dynamics research group at the Institute of Molecular and Translational Medicine.

Researcher with extensive expertise in DNA replication and the DNA damage response.

Author of 18 scientific publications, with more than 2300 citations and an h-index of 16.

Evaluator for national and international grant competitions and research assessment.

Reviewer for international peer-reviewed scientific journals.

Supervisor and mentor of Bachelor’s, Master’s, and PhD students.

 

Positions are available for motivated Master’s and PhD students interested in DNA replication and clinically relevant research aimed at improving PARP inhibitor therapy. Please contact me for further information.

Journals

CHROMÁ, K., Z. ŠKROTT, J. GURSKÝ, J. BACOVSKY, P. MOUDRÝ, T. BUCHTOVÁ, M. MISTRÍK, J. BÁRTEK
A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment. Cell Death & Disease. 2022, 13(3), 203, ISSN: 2041-4889, PMID: 35246527,
MOUDRÝ, P., K. CHROMÁ, S. BURSAC, S. VOLAREVIC, J. BÁRTEK
RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis. Cell Death and Differentiation. 2022, 29(3), 687-696, ISSN: 1350-9047, PMID: 34611297,
Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging. Aging-US. 2019, 11(8), 2512-2540, ISSN: 1945-4589, PMID: 31026227,

Doctoral mentorship

Omachelová Martina

Stress response of cancer cells

Status: Ongoing from 2024.

Master mentorship

Kopsová Barbora

Response of cells with BRCA2 deficiency to PARP inhibition and replication stress

Status: Ongoing from 2026.

Open positions

2 Molecular and Translational Medicine
Project: Cellular stress in health and disease
Supervisors: Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available: 3
Intended for: Doctoral training
Project: DNA replication in human pathophysiology
Supervisors: Moudrý Pavel Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position