Hajdúch Marián M.D., Ph.D.

User picture
Academic title: Associate Professor
Phone: +420 585632082, +420 585632083
Groups: IMTM, LEM, STAFF, SUPERVISOR

About me

Scientist and medical professional mainly involved in molecular and translational medicine (disease area oncology. rare and infectious diseases); long-term experience in project management; R&D and technology transfer activities, including the construction and management of large research infrastructures. Founding director of the Institute of Molecular and Translational Medicine, Palacky University in Olomouc, CZ. He has been involved as principal investigator, investigator or clinical site manager in 19 clinical trials; actively participated in the research and/or management of >50 national and international projects; established Cancer Research Czech Republic as a major charity to support cancer research in CZ; spin-off companies focused on manufacturing of molecular diagnostics, bioinformatics and drug development; leader/co-leader drug development initiatives with one registered drug on market, several products in clinical trials, >35 in vitro diagnostic products on market, several CE IVD certified. Former Chair of the Boards of National Director and current Czech National Director for European Translational Medicine Infrastructure (EATRIS-ERIC); participated in creation of national network for personalized medicine and cancer management policies. Published more than >350 papers, 21 books/chapters, >40 patents, >6700 SCI citations, H-index 41.

Journals

WITTERS, C., H. DE WINTER, M. LE COMPTE, M. ONDRA, D. LE BLON, B. VAN DEN BOGERD, C. DEBEN, M. HAJDÚCH, C. KOPPEN, H. VERCAMMEN
Forecasting a clear vision: How QSAR modeling catalyzes small molecule discovery in the field of corneal endothelial regeneration. SLAS Discovery : Advancing Life Sciences R & D. 2026, 100332, ISSN: 2472-5560, PMID: 42600746,  PDF.
SINKEVICIUTE, U., K. BURGETOVÁ JEČMEŇOVÁ, S. GURSKÁ, L. POSTOVA SLAVETINSKA, V. BARAN, P. POLISHCHUK, P. DŽUBÁK, M. HOCEK, M. HAJDÚCH, M. TICHÝ
Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases. ChemMedChem. 2026, 21(16), e70419, ISSN: 1860-7179, PMID: 42596056,  PDF.
KRASULOVÁ, K., B. NEUŽILOVÁ, K. DVOŘÁKOVÁ BENDOVÁ, K. HAJDUOVÁ, P. MLYNÁRČIK, M. POPPER, M. HAJDÚCH, M. PETŘÍK
Targeted PET Imaging of Pseudomonas aeruginosa Using a [68Ga]Ga-Pyoverdines Cocktail. Journal of Nuclear Medicine : official publication, Society of Nuclear Medicine. 2026, jnumed.125.271909, ISSN: 0161-5505, PMID: 42595487,  PDF.

Books & book chapters

DŽUBÁK, P., M. URBAN, M. HAJDÚCH
Vývoj nových léčiv, 1. vyd, Praha, Galén, 2015, 11, 469-472, ISBN: 978-80-7492-121-6,
HAJDÚCH, M., R. PYTLÍK
Biologická léčba v onkologii, 1. vyd, Praha, Grada Publishing, 2012, 2.7, 111-137, Dedication: BIOMEDREG CZ.1.05/2.1.00/01.0030, ISBN: 978-80-247-3727-0,
ŠÁNA, J., M. HAJDÚCH, O. SLABÝ
MicroRNA and Glial tumors: Tiny Relation with Great Potential, 1. vyd, Rijeka, InTech, 2012, 4, 59-74, Dedication: IGA NT/11214-4/2010, ISBN: 979-953-307-198-4,

Intellectual property

MEDIUM FOR TRANSPORTING AND STORING VIRUSES - PV 2020-665 (Hajdúch)
  1. Utility Model: CZ 35138. Granted: 8.6.2021. Ownership: Palacký University Olomouc; AUMED a.s. Inventors: HAJDÚCH Marián, DŽUBÁK Petr, JAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.
  2. Patent: CZ 309704. Granted: 9.8.2023. Ownership: Palacký University Olomouc; AUMED a.s. Inventors: HAJDÚCH Marián, DŽUBÁK Petr, JAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.
  3. Published Application EP 21213792.1 under EP 4012025 (15.6.2022)

Status: Available

N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE FOR TREATMENT OF CIRCADIAN RHYTHM DISEASES, DISORDERS AND DYSFUNCTIONS - PV 2019-757 (Voller) KINETIN
  1. Patent: CZ 310035. Granted: 18.4.2024. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  2. Published Application PCT/CZ2020/050094 under WO 2021/115502 (17.6.2021)
  3. Patent: US 12,558,358. Granted: 24.2.2026. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  4. Patent: EP 4072555. Granted: 22.1.2025. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav

Status: Available

MOLECULAR COMPLEX ASSEMBLY PARTICLES COMRISING BIS-R1, R2-DITHIOCARBAMATE-METAL COMPLEX AND A LIGAND, METHOD OF PREPARATION AND USE THEREOF - EP 18199181.1 (Mistrík) DISULFIRAM II
  1. Published Application EP 18199181.1 under EP 3636285 (15.4.2020)
  2. Published Application PCT/EP2019/077222 under WO 2020/074514 (16.4.2020)
  3. Patent: AU 2019358428. Granted: 17.11.2022. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  4. Patent: CA 3,114,031. Granted: 12.3.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  5. Patent: IL 281616. Granted: 2.4.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  6. Patent: US 12,303,531. Granted: 20.5.2025. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  7. Patent: JP 7220932. Granted: 3.2.2023. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  8. Patent: BR 1120210061703. Granted: 18.2.2026. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  9. Patent: MX 418,133. Granted: 29.10.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
  10. Patent: KR 10-2626651. Granted: 17.1.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián

Status: Available

Doctoral mentorship

Bačová Zuzana M.Sc.

Detection and clinical importance of circulating tumor cells in solid tumours

Status: Ongoing.

Uvírová Magdalena Ph.D.

Molecular genetic studies of selected solid tumors

Status: Graduated from 2011 to 2016.

Petrovičová Ivana

Detection of molecular cytogenetic abnormalities

Open positions

1 Molecular and cellular biology
Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
1 Medical chemistry and clinical biochemistry
Project: Research and development of small-molecule drugs
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
2 Biomarkers: Identification and validation
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
3 Chemical biology and experimental therapeutics
Project: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Supervisors: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
1 Bioinformatics / Chemoinformatics
Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
16 Molecular and Translational Medicine
Project: Identification of molecular targets and mechanisms of resistance in anticancer drugs using cell biology and proteomics
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Bioinformatics processing of large datasets in clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 positions (full-time or part-time)
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 full-time positions
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Biologically active molecules and their therapeutic combinations
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: New diagnostic, prognostic, and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 positions (full-time or part-time)

WHERE TO FIND US

Hněvotínská 1333/5
779 00 Olomouc
Czech Republic

+420 585632111
+420 585632180
recepce.umtm@upol.cz
info@imtm.cz

GPS: 49° 35´ 10.1869512" N, 17° 14´ 6.292305" E

ABOUT IMTM

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