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Džubák Petr M.D., Ph.D.

Journals

Autophagy revealed as a targetable vulnerability in senescent cells by cell painting phenotypic profiling: a mechanistic study of MCOPPB and related compounds. Geroscience. 2026, ISSN: 2509-2723, PMID: 42062708,  PDF.
TANGALLAPALLI, S., R. GUNDLA, K. PAIDIKONDALA, S. GURSKÁ, N. RAMPEESA, S. ANUGU, P. DŽUBÁK, M. HAJDÚCH, V. DAS, N. KATARI
Design, synthesis, and biological evaluation of novel 3-oxo-2,3-dihydropyridazine derivatives as interleukin-2-inducible T-cell kinase (ITK) inhibitors. RSC advances. 2025, 15(55), 47565-47586, ISSN: 2046-2069, PMID: 41356712,  PDF.
Synthesis and biological evaluation of novel C-30 modified lupane triterpenoids selectively cytotoxic against cancer cells. European Journal of Medicinal Chemistry. 2025, 302 (Pt 1), 118268, ISSN: 0223-5234 , PMID: 41124881,  PDF.

Books & book chapters

Detection and quantification of cellular antigens using flow cytometry, 1.vyd., Olomouc, Palacky University, 2021, 28, 209-214, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Hmotnostní spektrometrie, 1. vyd, korigovaný dotisk, Olomouc, Univerzita Palackého v Olomouci, 2021, 2.2, 34-42, ISBN: 978-80-244-3951-8,

Intellectual property

METHOD FOR NON-INVASIVE ASTHMA TREATMENT STRATIFICATION - EP 25223197.2 (Džubák)
  1. Filed Application EP 25223197.2

    Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, VÁCLAVKOVÁ Jana, KOUŘILOVÁ Pavla, KOPŘIVA František.

    Status: Patent pending

RNA ISOLATION KIT - PUV 2020-38366 (Džubák)
  1. Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, GURSKÁ Soňa, KOUDELÁKOVÁ Vladimíra, JAWOREK Hana.

Status: Available

MEDIUM FOR TRANSPORTING AND STORING VIRUSES - PV 2020-665 (Hajdúch)
  1. Utility Model: CZ 35138. Granted: 8.6.2021. Ownership: Palacký University Olomouc; AUMED a.s. Inventors: HAJDÚCH MariánDŽUBÁK PetrJAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.
  2. Patent: CZ 309704. Granted: 9.8.2023. Ownership: Palacký University Olomouc; AUMED a.s. Inventors: HAJDÚCH MariánDŽUBÁK PetrJAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.
  3. Published Application EP 21213792.1 under EP 4012025 (15.6.2022)

Status: Available

Postdoctoral mentorship

Znojek Pawel Ph.D.

HCT/HCA assays development

Status: Ongoing from 2013 to 2015.

Doctoral mentorship

Burgetová Ječmeňová Kateřina

Drug resistance mechanisms in cancer

Status: Ongoing from 2020.
Kotulová Jana Ph.D.

Identification of adenosine receptor modulators and their anticancer properties

Status: Graduated from 2014 to 2022.
Stanková Jarmila

Cytotoxic drugs molecular target identification by methods of cell biology and proteomics

Status: Graduated from 2016 to 2024.

Master mentorship

Burgetová Ječmeňová Kateřina

Development and characterization of resistant cell lines to purine and pyrimidine cytotoxic drugs

Status: Graduated from 2018 to 2020.
Růžičková Eliška B.Sc.

Evaluation of biological activity of demethylation drugs

Status: Graduated from 2013 to 2014.
Pastorková Barbora B.Sc.

Identification of molecular targets of anticancer drugs by immuno-affinity purification

Status: Graduated from 2013 to 2014.

Bachelor mentorship

Lónová Kateřina

Development and basic characterization of the cell line resistant to the CDK inhibitors

Status: Graduated from 2015 to 2016.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training