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Krasulová Kristýna Ph.D.
Akademický titul:
RNDr.
E-mail:
kristyna.krasulova@upol.cz
Telefon:
+420 585 632 138
Skupiny:
ÚMTM, LEM, POSTDOKTORSKÝ STUDENT, PERSONÁL
Postdoctoral training
Stav:
Probíhající.
O mně
I am a researcher specializing in the field of nuclear medicine and pharmacy, with a primary research focus on the preparation and analysis of radiolabeled compounds for advanced imaging techniques such as microPET, SPECT, MRI, and CT. I am doing biodistribution studies of radiolabeled compounds in vivo and investigating the behaviour of these compounds in vitro. Before my work in nuclear medicine and pharmacy, I had a background in molecular toxicology and pharmacology. I concentrated on elucidating transcriptional regulatory mechanisms related to drug metabolism and the processing of environmental pollutants.
Journals
In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A.
Xenobiotica.
2018,
49(1),
36-42,
ISSN: 0049-8254,
PMID: 29320899,
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity.
Molecules.
2017,
22(11),
pii: E1879,
ISSN: 1420-3049,
PMID: 29099769,
The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.
Chemico-biological Interactions.
2017,
278,
123-128,
ISSN: 0009-2797,
PMID: 29074051,