
Purchased: 2018
Latest upgrade: January 2021 – Airy Scan, additional lasers
Responsible person: Dr. Martin Mistrik (martin.mistrik@upol.cz)
Technology: Laser scanning confocal microscope Zeiss LSM980
Special features:
Established techniques:
Selected publications using the technology:
Aging (Albany NY). 2021 Dec 6;13(23):25004-25024. doi: 10.18632/aging.203744. Epub 2021 Dec 6.
Mol Oncol. 2021 Oct 10. doi: 10.1002/1878-0261.13114. Online ahead of print.
Nat Commun. 2021 Jan 29;12(1):713. doi: 10.1038/s41467-021-20989-9.
Purchased: 2018
Latest upgrade: January 2021 – Airy Scan, additional lasers
Responsible person: Dr. Martin Mistrik (martin.mistrik@upol.cz)
Technology: Laser scanning confocal microscope Zeiss LSM780
Special features:
Established techniques:
Seelected publications using the technology:
Nat Commun. 2021 Jan 29;12(1):713. doi: 10.1038/s41467-021-20989-9.
Cells. 2020 Feb 18;9(2):469. doi: 10.3390/cells9020469.
Oncogene. 2019 Oct;38(40):6711-6722. doi: 10.1038/s41388-019-0915-2. Epub 2019 Aug 7.
DNA Repair (Amst). 2019 Jun;78:114-127. doi: 10.1016/j.dnarep.2019.04.001. Epub 2019 Apr 6. Prostate. 2019 Mar;79(4):352-362. doi: 10.1002/pros.23741. Epub 2018 Nov 29.
Nature. 2017 Dec 14;552(7684):194-199. doi: 10.1038/nature25016. Epub 2017 Dec 6.
Nature. 2017 Dec 14;552(7684):194-199. doi: 10.1038/nature25016. Epub 2017 Dec 6.
Oncogene. 2017 Apr 27;36(17):2405-2422. doi: 10.1038/onc.2016.392. Epub 2016 Nov 14.
J Proteome Res. 2016 Dec 2;15(12):4505-4517. doi: 10.1021/acs.jproteome.6b00622. Epub 2016 Nov 9
Sci Rep. 2016 Jan 18;6:19567. doi: 10.1038/srep19567.
Nat Protoc. 2015 Aug;10(8):1248-63. doi: 10.1038/nprot.2015.083. Epub 2015 Jul 23.
Cell. 2014 Jul 31;158(3):633-46. doi: 10.1016/j.cell.2014.05.046.
Biol Reprod. 2014 Jun;90(6):124. doi: 10.1095/biolreprod.114.118497. Epub 2014 Apr 30.
Plant Physiol. 2014 May;165(1):129-48. doi: 10.1104/pp.114.238477. Epub 2014 Mar 31.
Purchased: 2011
Latest upgrade: January 2018 – Super-sensitive camera
Responsible person: Dr. Martin Mistrik (martin.mistrik@upol.cz)
Technology: Zeiss laser-based fluorescent microscope with Yokogawa spinning disk confocal unit
Special features:
Established techniques:
Selected publications using the technology:
Aging (Albany NY). 2021 Dec 6;13(23):25004-25024. doi: 10.18632/aging.203744. Epub 2021 Dec 6.
DNA Repair (Amst). 2019 Jun;78:114-127. doi: 10.1016/j.dnarep.2019.04.001. Epub 2019 Apr 6.
J Proteome Res. 2016 Dec 2;15(12):4505-4517. doi: 10.1021/acs.jproteome.6b00622. Epub 2016 Nov 9.
Purchased: 2008
Latest upgrade: 2016 – new software
Responsible person: Dr. Martin Mistrik (martin.mistrik@upol.cz)
Technology: Olympus fluorescent microscope designed for high content and high throughput microscopy
Special features:
Established techniques:
Selected publications using the technology:
Cell Death Dis. 2022 Mar 4;13(3):203. doi: 10.1038/s41419-022-04651-w.
Cell Death Differ. 2022 Mar;29(3):687-696. doi: 10.1038/s41418-021-00882-0. Epub 2021 Oct 5.
Nature. 2018 Jul;559(7713):279-284. doi: 10.1038/s41586-018-0261-5. Epub 2018 Jun 27.
Nature. 2017 Dec 14;552(7684):194-199. doi: 10.1038/nature25016. Epub 2017 Dec 6.
Cell Cycle. 2018;17(1):92-101. doi: 10.1080/15384101.2017.1403685. Epub 2017 Dec 10.
Oncogene. 2017 Apr 27;36(17):2405-2422. doi: 10.1038/onc.2016.392. Epub 2016 Nov 14.
Nature. 2015 May 28;521(7553):541-544. doi: 10.1038/nature14328. Epub 2015 Mar 23.
Cell Rep. 2015 Mar 17;10(10):1749-1757. doi: 10.1016/j.celrep.2015.02.028. Epub 2015 Mar 12.
Nat Commun. 2014 Nov 5;5:5348. doi: 10.1038/ncomms6348.
Cancer Res. 2011 Mar 15;71(6):2129-39. doi: 10.1158/0008-5472.CAN-10-2684.
J Cell Biol. 2009 Sep 7;186(5):655-63. doi: 10.1083/jcb.200812138.
Purchased: 2011
Latest upgrade:
Responsible person: Dr. Hana Kolářová (hana.kolarova@upol.cz )
Technology: Olympus Atomic force microscope
Special features:
Established techniques:
Selected publications using the technology:
Photodiagnosis and Photodynamic Therapy; 2021 34:102224. doi: 10.1016/j.pdpdt.2021.102224
Scientific Reports; 2021 11:6786. doi: 10.1038/s41598-021-85828-9
Cells Tissues Organs 2020 209(4-6):177-188. doi: 10.1159/000512807. Epub 2021 Feb 15.
Appl Immunohistochem Mol Morphol. 2020 Feb;28(2):166-174. doi: 10.1097/PAI.0000000000000689
Microscopy and Microanalysis 2020 26:139–147. doi:10.1017/S1431927619015113
Lekar a technika – Clinician and Technology 2020 50(3):114–121. doi: 10.14311/CTJ.2020.3.05
Lekar a technika – Clinician and Technology 2019 49(2):41-45. doi: 10.14311/CTJ.2019.2.01
Cells Tissues Organs 2019;208:37–47. doi: 10.1159/000506735
Purchased: 2012
Latest upgrade: 2014 – TrueSurface module
Responsible person: Dr. Václav Ranc (vaclav.ranc@upol.cz), since 06.2021
Technology: Olympus LSM microcope with WITec Raman detector module
Special features:
Established techniques:
Selected publications using the technology:
Medvedikova, M., Ranc, V., Vanco, J., Travnicek, Z., Anzenbacher, P., Effect of copper(II) mixed-ligand quinolinonato complexes on the activity of selected cytochromes P450, Journal of biological inorganic chemistry, submitted.
Ranc V., Kalita, O., Pavlacka, O., Vaverka, M., Discrimination of resected glioma tissue using surface enhanced Raman spectroscopy and Au@ZrO2 nanocomposite, Frontiers in chemistry, in preparation.
Purchased: 2022
Latest upgrade:
Responsible person: Dr. Miloš Petřík (milos.Petrik@seznam.cz),
Technology: Hybrid PET/MRI small animal imaging systems by Mediso
Special features:
Established techniques: in vivo cancer studies for mouse and rat involving:
Selected publications using the technology:
Responsible person: Martin Mistrik Ph.D.
Responsible person: Dr. Václav Ranc (vaclav.ranc@upol.cz), since 06.2021