Džubák Petr M.D., Ph.D.

Journals

KAZAKOVA, A., I. FRYDRYCH, N. JAKUBCOVÁ, J. POKORNÝ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.
STANKOVÁ, J., M. JURÁŠEK, M. HAJDÚCH, P. DŽUBÁK
Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties. Journal of Natural products. 2024, 87(4), 1306-1319, ISSN: 0163-3864, PMID: 38482846,  PDF.
VELAVAPALLI, V., V. MADDIPATI, S. GURSKÁ, N. ANNADURAI, B. LIŠKOVÁ, N. KATARI, P. DŽUBÁK, M. HAJDÚCH, V. DAS, R. GUNDLA
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation. ACS Omega. 2024, 7(9), 8067-8081, ISSN: 2470-1343, PMID: 38405484,  PDF.

Books & book chapters

DRÁBEK, J., J. BERKOVCOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. KHOYLOU, V. KOUDELÁKOVÁ, J. SROVNAL, M. STAŇKOVÁ, R. TROJANEC
Detekce nádorových biomarkerů v molekulárně biologické laboratoři, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2012, 144 s, Dedication: MOLONKOL CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3002-7,
ŠAREK, J., M. KVASNICA, M. VLK, M. URBAN, P. DŽUBÁK, M. HAJDÚCH
The Potential of Triterpenoids in the Treatment of Melanoma, 1.vyd, Rijeka, InTech, 2011, 7, 125-158, Dedication: 305/09/1216, ISBN: 978-953-307-293-7,

Intellectual property

SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Patent: CZ 307334. Granted: 2.5.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  2. Published application PCT/CZ2017/050031 under WO 2018/024265 (8.2.2018)
  3. Patent: EP 3494122. Granted: 18.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  4. Patent: US 10,730,905. Granted: 4.8.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  5. Patent: JP 6685475. Granted: 2.4.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
  6. Patent: CA 3.031.049. Granted: 7.7.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián

Status: Available

FLUORESCENT DERIVATIVE FOR NON-CATALYTIC LABELING OF NUCLEIC ACID AND PEPTIDE COMPONENTS (Jedináková)
  1. Utility Model: CZ 30136, Granted: 13.12.2016, Ownership: Palacký University Olomouc, Inventors: Jedináková Petra, Hlaváč Jan, Václavková Jana, Konečný Petr, Džubák Petr, Hajdúch Marián

Status: Terminated

SUBSTITUTED THIENOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
  2. Patent: EP 3478701. Granted: 10.8.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  3. Patent: US 10,414,788. Granted: 17.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  4. Patent: JP 6650074. Granted: 21.1.2020.  Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  5. Patent: CA 3.029.170. Granted: 16.2.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University, Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr

Status: Terminated

Doctoral mentorship

Holub Dušan Ph.D.

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS

Status: Graduated from 2009 to 2016.
Václavková Jana M.Sc.

Identification of mechanisms of action of molecules with anticancer effect

Status: Graduated from 2014 to 2021.
Hrubá Lenka RNDr., Ph.D.

Mechanism of multidrug resistance (MDR) in cancer cells

Status: Graduated from 2015 to 2023.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study