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Hrubá Lenka RNDr., Ph.D.

Journals

DAS, V., J. MILLER, C. ALLADI, N. ANNADURAI, J. DE SANCTIS, L. HRUBÁ, M. HAJDÚCH
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies. Medicinal Research Reviews. 2024, ISSN: 0198-6325, PMID: 38530106,  PDF.
Nucleoside-based anticancer drugs: mechanism of action and drug resistance. Biochemical Pharmacology. 2023, ISSN: 0006-2952 , PMID: 37567317,  PDF.
JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR, P. DŽUBÁK
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN: 0045-2068, PMID: 36592487,  PDF.

Books & book chapters

Functional test of MDR transporters, 1.vyd., Olomouc, Palacky University, 2021, 30, 223-230, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Master mentorship

Danišková Andrea

Identification of CDK kinase inhibitors using mass spectrometry

Status: Graduated from 2020 to 2022.

Bachelor mentorship

Sapíková Michaela

In vitro models of drug resistance in oncology

Status: Graduated from 2021 to 2023.
Hrašnová Patrícia

Enzymatic assay

Status: Graduated from 2018 to 2020.
Klibrová Vendula

Development and basic characterization of the cell line resistant to the disulfiram metabolite

Status: Graduated from 2019 to 2021.