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Academic title: Mgr
Phone: +420 585632234
Groups: EXSTAFF, IMTM, LIG, POSTDOCTORAL FELLOW

Postdoctoral training

Status: Ongoing.

About me

My research is focused on mechanisms of DNA damage response (DDR) in connection to either disrupted protein homeostasis or DNA replication. Another aspect of my study aims at understanding of cancer cell vulnerabilities for better guidance of existing anticancer treatments as well as the drug-repurposing strategies.

Journals

MAJERA, D., Z. ŠKROTT, K. CHROMÁ, J. MERCHUT-MAYA, M. MISTRÍK, J. BÁRTEK
Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway. Cells. 2020, 9(2), pii: E469, ISSN: 2073-4409, PMID: 32085572,  PDF.
VESELÁ, E., K. CHROMÁ, Z. TURI, M. MISTRÍK
Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies. Biomolecules. 2017, 7(1), pii: E19, ISSN: 2218-273X, PMID: 28230817,  PDF.
CHROMÁ, K., M. MISTRÍK, P. MOUDRÝ, J. GURSKÝ, M. LIPTAY, R. STRAUSS, Z. ŠKROTT, R. VRTEL, J. BARTKOVA, J. KRAMARA, J. BÁRTEK
Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress. Oncogene. 2017, 36(17), 2405-2422, ISSN: 0950-9232, PMID: 27841863,