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De Sanctis Juan Bautista Ph.D.
About me
I was initially formed in Biochemistry (Temple University), and then I did doctoral studies in physiological sciences, specialising in Biochemistry, Metabolism and immunology. I was a professor for more than 30 years at the Faculty of Medicine and the Institute of Immunology of the Faculty of Medicine of Universidad Central de Venezuela. My big area of expertise is inflammation, with ample background in immune response, cell metabolism, lipidomic, signal transduction and pharmacology. Currently, I am involved in a project on Cancer and immune response and others in Covid and long Covid (pending funding).
Journals
The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide.
Cellular and Molecular Life Sciences.
2020,
77(21),
4255-4267,
ISSN: 1420-682X,
PMID: 32394023,
Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis.
Lung.
2020,
198(3),
459-469,
ISSN: 0341-2040,
PMID: 32306138,
Treatment of Allergic Asthma With Fenretinide Formulation (LAU-7b) Downregulates ORMDL Sphingolipid Biosynthesis Regulator 3 ( Ormdl3) Expression and Normalizes Ceramide Imbalance.
The Journal of Pharmacology and Experimental Therapeutics.
2020,
373(3),
476-487,
ISSN: 0022-3565,
PMID: 32273303,
Open positions
| Project: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Supervisors: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| Available: | 5 |
| Intended for: | Doctoral training |