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Holub Dušan Ph.D.
Academic title:
M.Sc.
E-mail:
dusan.holub@upol.cz
Phone:
+420 585632068, +420 585632069
Groups:
DOCTORAL STUDENT, IMTM, LEM, STAFF
Doctoral training
Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS
Hepcidin, a 25 amino acid peptide, plays an important role in iron homeostasis. As such, it has potential as an indicator of any iron-related condition, such as anemia. My research focuses on the measurement of hepcidin in biological fluids to improve our understanding of iron-related disorders. A possible result of such studies could be the development of hepcidin as a tool for diagnosis and clinical management of such disorders.
Specialization:
Oncology
Supervisor:
Džubák Petr M.D., Ph.D.
Status:
Graduated from 2009 to 2016.
Journals
Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.
Journal of Proteomics.
2017,
162,
73-85,
ISSN: 1874-3919,
PMID: 28478306,
Characterization of iron metabolism and erythropoiesis in erythrocyte membrane defects and thalassemia traits.
Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic.
2015,
160(2),
231-237,
ISSN: 1213-8118,
PMID: 26592557,
Affinity-Based Methods in Drug-Target Discovery.
Current Drug Targets.
2015,
16(1),
60-76,
ISSN: 1389-4501,
PMID: 25410410,