Contakt

Václavková Jana M.Sc.

E-mail: jana.vaclavkova02@upol.cz
Phone: +420 585 632 069

Ph.D. student working on: Identification of mechanisms of action of molecules with anticancer effect by proteomic methods

- drug affinity responsive target stability (DARTS) and affinity purification methods

- high performance liquid chromatography - mass spectrometry (HPLC/MS)

Proteomic profiling studies - HPLC/MS

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publications (Impact Factor Journals)

  • [2]
    ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715
  • [1]
    OŽDIAN, T., D. HOLUB, Z. MACEČKOVÁ, L. VARANASI, G. RYLOVÁ, J. ŘEHULKA, J. VÁCLAVKOVÁ, H. SLAVÍK, P. MOUDRÝ, P. ZNOJEK, J. STANKOVÁ, J.B. DE SANCTIS, M. HAJDÚCH a P. DŽUBÁK. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells. Journal of Proteomics. 2017, 162, 73-85. ISSN 1874-3919 . IF: 3.867. PMID: 28478306
  • Publications (Other Reviewed Journals)

  • [2]
    KULTAN, J., V. KOLEK, P. DŽUBÁK, J. VÁCLAVKOVÁ, M. HAJDÚCH a M. SZKORUPA. Možnosti neinvazivní detekce karcinomu plic. Studia Pneumologica et Phthiseologica. 2018, 78(3), 69-75. ISSN 1213-810X.
  • [1]
    OŽDIAN, T., D. HOLUB, G. RYLOVÁ, J. VÁCLAVKOVÁ, M. HAJDÚCH a P. DŽUBÁK. Porovnání hmotnostně spektrometrických přístupů v proteomickém profilování léčiv. Chemagazín. 2016, 5, 8-11. ISSN 1210-7409.

  • Patents, Utility models & other IP's :

    [1] FLUORESCENT DERIVATIVE FOR NON-CATALYTIC LABELING OF NUCLEIC ACID AND PEPTIDE COMPONENTS, PUV 2016-32558
    1. Utility Model: CZ 30 136, Granted: 13. 12. 2016, Ownership: Palacky University, Olomouc, Inventors: Jedináková Petra, Hlaváč JanVáclavková Jana, Konečný Petr, Džubák Petr, Hajdúch Marián

    Status: Available



    Master students mentor:

    [1] Eva Neubauerová, Identification of molecular targets by proteomic methods,
    status: Graduated, from: 2014 to 2016


    Bachelor students mentor:

    [1] Zuzana Machačová, Identification of Proteomic Molecular Targets of Biologically Active Molecules,
    status: Graduated, from: 2017 to 2019