Header image
Kotková Lucie
Akademický titul:
Mgr
E-mail:
lucie.kotkova01@upol.cz
Telefon:
605882878
Skupiny:
DOKTORSKÝ STUDENT, ÚMTM, LEM, PERSONÁL
Doktorské studium
Genetic and Epigenetic Biomarkers in cancer
Specializace:
Pediatrie
Vedoucí:
Drábek Jiří Ph.D.
Stav:
Probíhající od 2017.
O mně
Researcher and Ph.D. candidate
My undergraduate studies were focused on cancer genetics, with a bachelor's thesis "Molecular and genetic changes in glial tumours" and a master's thesis "Optimization of library technology for multi-parallel sequencing in the colorectal cancer diagnostics".
Now, my main research lies in the field of forensic epigenomics, especially DNA phenotyping and visual characteristic predictions.
I work on developing a model capable of predicting the age of an unknown person based on their DNA extracted from blood or semen samples. My main laboratory tools are bisulfite conversion and its alternatives, qPCR and multiparallel sequencing.
Journals
Development and extensive analytical validation of deep amplicon sequencing for detecting KRAS and NRAS mutations in metastatic colorectal cancer samples.
Neoplasma.
2021,
69(1),
203-2015,
ISSN: 0028-2685,
PMID: 34881628,
Age-related changes in sperm DNA methylation and their forensic and clinical implications.
Epigenomics.
2023,
ISSN: 1750-1911,
PDF.
Copy number variation and clinical response to chemotherapy and bevacizumab in the Czech metastatic colorectal cancer patients.
Klinická Onkologie.
2024,
38(4),
277-285,
ISSN: 0862-495X.
Books & book chapters
Vybrané metody forenzní genetiky,
1.vyd.,
Olomouc,
Palacky University,
2022,
1 s,
ISBN: 978-80-244-6177-9,
Determination of length of nucleic acid fragments by digital capillary electrophoresis,
1.vyd.,
Olomouc,
Palacky University,
2021,
50,
399-408,
Dedication: LO1304,
ISBN: 978-80-244-6049-9,