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Hajdúch Marián M.D., Ph.D.

Journals

Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.
VERCAMMEN, H., M. ONDRA, J. KOTULOVÁ, E. DE LA HOZ, C. WITTERS, K. JEČMEŇOVÁ, M. LE COMPTE, C. DEBEN, S. DHUBHGHAILL, C. KOPPEN, M. HAJDÚCH, B. VAN DEN BOGERD
"Keep on ROCKIn": Repurposed ROCK inhibitors to boost corneal endothelial regeneration. Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 2024, 174, 116435, ISSN: 0753-3322, PMID: 38513591,  PDF.
Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties. Journal of Natural products. 2024, ISSN: 0163-3864, PMID: 38482846,  PDF.

Books & book chapters

Vývoj nových léčiv, 1. vyd, Praha, Galén, 2015, 11, 469-472, ISBN: 978-80-7492-121-6,
HAJDÚCH, M., R. PYTLÍK
Biologická léčba v onkologii, 1. vyd, Praha, Grada Publishing, 2012, 2.7, 111-137, Dedication: BIOMEDREG CZ.1.05/2.1.00/01.0030, ISBN: 978-80-247-3727-0,
ŠÁNA, J., M. HAJDÚCH, O. SLABÝ
MicroRNA and Glial tumors: Tiny Relation with Great Potential, 1. vyd, Rijeka, InTech, 2012, 4, 59-74, Dedication: IGA NT/11214-4/2010, ISBN: 979-953-307-198-4,

Intellectual property

MEDIUM FOR TRANSPORTING AND STORING VIRUSES (Hajdúch)

Utility Model: CZ 35138. Granted: 8.6.2021. Ownership: Palacký University Olomouc. Inventors: HAJDÚCH MariánDŽUBÁK PetrJAWOREK Hana, BOUŠKA Ondřej, KUBÁŇOVÁ Kateřina, VRONKA Juraj.

Status: Available

SURFACE MODIFIED PARTICLES (Cígler)
  1. Patent: CZ 309422. Granted: 28.12.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: CÍGLER Petr, NEBURKOVÁ Jitka, SCHIMER Jiří, GURICOVÁ Miroslava, HAJDÚCH MariánJAWOREK HanaONDRA MartinKUBÍČKOVÁ Agáta 
  2. Published Application PCT/CZ2021/050103 under WO 2022/068982 (7.4.2022)

Status: Available

1,2-DITHIOLANE COMPOUND FOR METAL SURFACE MODIFICATION (Cígler)

Utility Model: CZ 34573. Granted: 24.11.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HAJDÚCH Marián, JAWOREK Hana, ONDRA Martin, KUBÍČKOVÁ Agáta

Status: Available

Doctoral mentorship

Bačová Zuzana M.Sc.

Detection and clinical importance of circulating tumor cells in solid tumours

Status: Ongoing.
Uvírová Magdalena Ph.D.

Molecular genetic studies of selected solid tumors

Status: Graduated from 2011 to 2016.
Petrovičová Ivana

Detection of molecular cytogenetic abnormalities

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Supervisors: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Biologically active molecules and their therapeutic combinations
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training