Lukáč Dávid MSc

E-mail: david.lukac01@upol.cz

Phone: +421911438047

Groups: DOCTORAL STUDENT, EXSTAFF, IMTM, LIG

DNA replication and cancer

Specialization: Medical genetics

Supervisor: Moudrý Pavel Ph.D.

Status: Graduated from 2020 to 2025.

PhD student in the 4th year of study, and a member of the DNA Replication Dynamics group. Specializing in the DNA replication machinery in cancer cell lines, with a focus on replication stress and replication stress responses caused by PARP inhibitors (PARPi). We investigate these processes using various approaches, including advanced laser microscopy methods, cell cultures, and immunoblotting.

LUKÁČ, D., K. CHROMÁ, P. MOUDRÝ

The need for speed: drivers and consequences of accelerated replication forks. Communications Biology. 2025, 8(1), 1538, ISSN: 2399-3642, PMID: 41198817, PDF.

MACHAČOVÁ, Z., K. CHROMÁ, D. LUKÁČ, I. PROTIVÁNKOVÁ, P. MOUDRÝ

DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps. Nature Communications. 2024, 15(1), 7375, ISSN: 2041-1723, PMID: 39191785, PDF.

BUCHTOVÁ, T., D. LUKÁČ, Z. ŠKROTT, K. CHROMÁ, J. BÁRTEK, M. MISTRÍK

Drug-Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics. International Journal of Molecular Sciences. 2023, 24(3), 2885, ISSN: 1422-0067, PMID: 36769206, PDF.

Kočářová Natálie

Effect of olaparib on DNA damage signalling

Status: Graduated from 2023 to 2024.

Lukáč Dávid MSc

Doctoral training

About me

Journals

Bachelor mentorship

Kočářová Natálie