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Dömling Alexander PhD.
Journals
        Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.        
                  Nature Communications.                
                  2023,
                
                              14(1),
                  
                              8437,
                          
                  ISSN: 2041-1723,
                
                
                              PMID: 38114468,                          
                 
                          
        
      
    
        Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors.        
                  Journal of Medicinal Chemistry.                
                  2023,
                
                              66(14),
                  
                              9577-9591,
                          
                  ISSN: 0022-2623,
                
                
                              PMID: 37450644,                          
                 
                          
        
      
    Open positions
| Projekt: | New anti-inflammatory small molecules | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Microsynthesis of drug candidates in medicinal chemistry | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 2 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 2 places in full-time study | 
| Projekt: | Innovative approaches to modifiers of protein interactions | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Utilization of the space of unprecedented covalent inhibitors | 
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Discovery of new antibacterial substances | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Discovery of new antitumor substances | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Innovative drugs for Parkinson's disease | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Innovative medicinal chemistry | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Decoding the binding principles of small molecules to RNA | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Targeted approaches to covalent inhibitors | 
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation | 
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Modification of biologically active molecules leading to their improvement pharmacological properties | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 2 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 2 places in full-time study | 
| Projekt: | New methods of targeted protein degradation | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Drug repurposing for the treatment and prevention of diseases | 
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | New chemoinformatic approaches to fragment-based drug discovery | 
|---|---|
| Vedoucí: | Dömling Alexander PhD. | 
| K dispozici: | 1 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 1 place in full-time study | 
| Projekt: | Development of drugs in the field of small molecules 2 places in full-time study | 
|---|---|
| Vedoucí: | Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D. | 
| K dispozici: | 2 | 
| Určeno pro: | Doktorské studium | 
| Souhrn: | 2 places in full-time study | 
 
         
               
              