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Řehulka Jiří Ph.D.

Journals

Novel C-2 Aromatic Heterocycle-Substituted Triterpenoids Inhibit Hedgehog Signaling in GLI1 Overexpression Cancer Cells. ACS Omega. 2025, 10(10), 10617-10632, ISSN: 2470-1343, PMID: 40124057,  PDF.
ŘEHULKA, J., M. JURÁŠEK, P. DRABER, A. IVANOVA (NIKONENKO), S. GURSKÁ, K. JEČMEŇOVÁ, O. MOKSHYNA, M. HAJDÚCH, P. POLISHCHUK, P. DRAŠAR, P. DŽUBÁK
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Journal of enzyme inhibition and medicinal chemistry. 2024, 39(1), 2367139, ISSN: 1475-6366 , PMID: 38904149,  PDF.
JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR, P. DŽUBÁK
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN: 0045-2068, PMID: 36592487,  PDF.

Books & book chapters

Immunofluorescence staining of intracellular protein targets , 1.vyd., Olomouc, Palacky University, 2021, 16, 111-118, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Intellectual property

PYRROLOQUINOLINES AND THEIR USE AS TUBULINE ASSEMBLY INHIBITORS (Soural)
  1. Published Application PCT/CZ2023/050038 under WO 2025/008012 (9.1.2025)

Bachelor mentorship

Oravcová Alexandra

Identification of small molecule cell cycle modulators

Stav: Absolvoval od 2021 do 2022.
Kejklíčková Kateřina

Optimization of the cellular model for the study of RAN translation modulators

Stav: Probíhající od 2025.