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Hajdúch Marián M.D., Ph.D.
Akademický titul:
Associate Professor
E-mail:
marian.hajduch@upol.cz
Telefon:
+420 585632082, +420 585632083
Skupiny:
ÚMTM, LEM, PERSONÁL, VEDOUCÍ
O mně
Scientist and medical professional mainly involved in molecular and translational medicine (disease area oncology. rare and infectious diseases); long-term experience in project management; R&D and technology transfer activities, including the construction and management of large research infrastructures. Founding director of the Institute of Molecular and Translational Medicine, Palacky University in Olomouc, CZ. He has been involved as principal investigator, investigator or clinical site manager in 19 clinical trials; actively participated in the research and/or management of >50 national and international projects; established Cancer Research Czech Republic as a major charity to support cancer research in CZ; spin-off companies focused on manufacturing of molecular diagnostics, bioinformatics and drug development; leader/co-leader drug development initiatives with one registered drug on market, several products in clinical trials, >35 in vitro diagnostic products on market, several CE IVD certified. Former Chair of the Boards of National Director and current Czech National Director for European Translational Medicine Infrastructure (EATRIS-ERIC); participated in creation of national network for personalized medicine and cancer management policies. Published more than >350 papers, 21 books/chapters, >40 patents, >6700 SCI citations, H-index 41.
Journals
CRISPR/Cas9 bioluminescence-based assay for monitoring CFTR trafficking to the plasma membrane.
Life Science Alliance.
2023,
7(1),
e202302045,
ISSN: 2575-1077,
PMID: 37918963,
Intellectual property
SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
- Patent: CZ 307334. Granted: 2.5.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
- Published application PCT/CZ2017/050031 under WO 2018/024265 (8.2.2018)
- Patent: EP 3494122. Granted: 18.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: US 10,730,905. Granted: 4.8.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: JP 6685475. Granted: 2.4.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: CA 3.031.049. Granted: 7.7.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
Status: Available
FLUORESCENT DERIVATIVE FOR NON-CATALYTIC LABELING OF NUCLEIC ACID AND PEPTIDE COMPONENTS (Jedináková)
- Utility Model: CZ 30136, Granted: 13.12.2016, Ownership: Palacký University Olomouc, Inventors: Jedináková Petra, Hlaváč Jan, Václavková Jana, Konečný Petr, Džubák Petr, Hajdúch Marián
Status: Terminated
SUBSTITUTED THIENOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
- Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
- Patent: EP 3478701. Granted: 10.8.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: US 10,414,788. Granted: 17.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: JP 6650074. Granted: 21.1.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: CA 3.029.170. Granted: 16.2.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University, Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
Status: Terminated
Doctoral mentorship
Lenart Lukáš M.Sc.
Molecular basis of rare diseases and molecular targets
Stav:
Probíhající od 2023.
Open positions
| Projekt: | Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Genetic and epigenetic biomarkers of cancer diseases |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D. |
| K dispozici: | 3 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 3 places in full-time or combined form of study |
| Projekt: | Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development |
|---|---|
| Vedoucí: | Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Antitumor drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Drug repurposing for the treatment and prevention of diseases |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Bioinformatics processing of big data within clinical and preclinical studies |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D. |
| K dispozici: | 3 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 3 places in full-time or combined form of study |
| Projekt: | Identification of molecular targets and mechanisms of resistance in antitumor drugs |
|---|---|
| Vedoucí: | Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Diagnosis and treatment of rare diseases |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Genetic and epigenetic biomarkers in health and disease |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |
| Projekt: | Physiology and pathophysiology of aging |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Anticancer drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Development of drugs in the field of small molecules 2 places in full-time study |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Identification of proteomic biomarkers in proximal fluids and tissues |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Biologically active molecules and their therapeutic combinations |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Vedoucí: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |