Džubák Petr M.D., Ph.D.

Journals

HRUBÁ, L., V. DAS, M. HAJDÚCH, P. DŽUBÁK
Nucleoside-based anticancer drugs: mechanism of action and drug resistance. Biochemical Pharmacology. 2023, ISSN: 0006-2952 , PMID: 37567317,  PDF.
IVASECHKO, I., A. LOZYNSKYI, J. SENKIV, P. ROSZCZENKO, Y. KOZAK, N. FINIUK, O. KLYUCHIVSKA, N. KASHCHAK, N. MANKO, Z. MASLYAK, D. LESYK, A. KARKHUT, S. POLOKVOVYCH, R. CZARNOMYSY, O. SZEWCZYK, A. KOZYTSKIY, O. KARPENKO, D. KHYLUK, A. GZELLA, K. BIELAWSKI, A. BIELAWSKA, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH, R. STOIKA, R. LESYK
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone). European Journal of Medicinal Chemistry. 2023, 252, 115304, ISSN: 0223-5234, PMID: 37001390,  PDF.
OŽDIAN, T., J. VODICKA, J. DOSTÁL, D. HOLUB, J. VÁCLAVKOVÁ, M. JESETA, B. HAMERNÍKOVÁ, P. KOUŘILOVÁ, O. MALCHAR, V. DVORAK, P. HEJTMANEK, K. SOBKOVA, P. VENTRUBA, R. PILKA, P. DŽUBÁK, M. HAJDÚCH
Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders. International Journal of Molecular Sciences. 2023, 24(2), 1038, ISSN: 1422-0067, PMID: 36674559,  PDF.

Intellectual property

15BETA-SUBSTITUTED ESTRONE DERIVATIVES AS SELECTIVE INHIBITORS OF 17BETA-HYDROXYSTEOID-DEHYDROGENASES, METHOD OF PREPARATION AND USE THEREOF (Kotora)
  1. Patent: CZ 307437. Granted: 11.7.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Helmholtz Zentrum Munchen GmbH, Institute of Molecular Genetics CAS, Palacký University Olomouc. Inventors: KOTORA Martin, PRCHALOVÁ Eva, ADAMSKI Jerzy, MOLLER Gabriele, ŠTĚPÁNEK Ondřej, BARTŮNĚK Petr, SEDLÁK David, DŽUBÁK Petr, HAJDÚCH Marián
  2. Published Application PCT/CZ2017/050022 under WO 2017/211330 (14.12.2017)
  3. Published Application EP 17731057.0 under EP 3464314 (10.4.2019)
  4. Published Application AU 2017/276477 under AU 2017276477 (29.11.2018)
  5. Published Application CA 3.026.704 under CA 3026704 (14.12.2017)
  6. Published Application US 2017/16305829 under US 2019330258 (31.10.2019)

​Status: Terminated 

CULTURE DISH (Džubák)
  1. Utility Model: CZ 28806. Granted: 10.11.2015. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  2. Patent: EP 3147347. Granted: 6.5.2020. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  3. Design: CZ 36622. Granted: 28.12.2015. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  4. Registered Community Design: RCD 003039577-0001. Granted: 23.3.2016. Ownership: Palacký University Olomouc, Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  5. Registered Community Design: RCD 003039577-0002. Granted: 23.3.2016. Ownership: Palacký University Olomouc, Inventors: DŽUBÁK Petr, HAJDÚCH Marián

Status: Terminated 

SUBSTITUTED 7-DEZAPURIN RIBONUCLEOSIDES (Hocek)
  1. Patent: CZ 305466. Granted: 7.9.2015. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián 
  2. Patent: JP 5485172. Granted: 7.5.2014. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián 
  3. Patent: US 9,586,986. Granted: 7.3.2017. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián
  4. Patent: AU 20142777740. Granted: 25.2.2016. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián

Status: Available

Doctoral mentorship

Oždian Tomáš Ph.D.

Cancer proteomics in clinical and experimental oncology

Stav: Absolvoval od 2009 do 2016.
Balatková Pavlína

Experimental development of drugs and nanoparticles targeting prototoxic stress

Stav: Probíhající od 2023.
Kroupová Denisa

Multi Omics analyzes of proximal fluids for the identification of novel biomarkers and molecular targets

Stav: Probíhající od 2023.

Open positions

Projekt: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Utilization of the space of unprecedented covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Vedoucí: Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Vedoucí: Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Genetic and epigenetic biomarkers of cancer diseases
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 places in full-time or combined form of study
Projekt: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Identification of proteomic biomarkers in tears of patients with brain cancer
Vedoucí: Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Antitumor drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Targeted approaches to covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Anticancer drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Genetic and epigenetic biomarkers in health and disease
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Identification of proteomic biomarkers in proximal fluids and tissues
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Omic approaches in reproductive medicine
Vedoucí: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study