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Holub Dušan Ph.D.
Akademický titul:
M.Sc.
E-mail:
dusan.holub@upol.cz
Telefon:
+420 585632068, +420 585632069
Skupiny:
DOKTORSKÝ STUDENT, ÚMTM, LEM, PERSONÁL
Doktorské studium
Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS
Hepcidin, a 25 amino acid peptide, plays an important role in iron homeostasis. As such, it has potential as an indicator of any iron-related condition, such as anemia. My research focuses on the measurement of hepcidin in biological fluids to improve our understanding of iron-related disorders. A possible result of such studies could be the development of hepcidin as a tool for diagnosis and clinical management of such disorders.
Specializace:
Onkologie
Vedoucí:
Džubák Petr M.D., Ph.D.
Stav:
Absolvoval od 2009 do 2016.
Journals
Cardiac amyloidosis: from clinical suspicion to morphological diagnosis.
Pathology.
2018,
50(3),
261-268,
ISSN: 0031-3025,
PMID: 29448998,
Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates.
American Journal of Respiratory Cell and Molecular Biology.
2018,
58(1),
55-65,
ISSN: 1044-1549,
PMID: 28850259,
Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin.
Blood cells, molecules & diseases.
2017,
69,
23-29,
ISSN: 1079-9796,
PMID: 28803808,