Bouchal Jan Ph.D.

Bouchal Jan Ph.D.'s picture
Phone: +420 585639570
Curriculum Vitae: download

Publications (Impact Factor Journals):

  • [28]
    REMSIK, J., L. BINO, Z. KAHOUNOVA, G. KHARAISHVILI, S. SIMECKOVA, R. FEDR, T. KUCIRKOVA, S. LENART, X. MURESAN, E. SLABAKOVA, L. KNOPFOVA, J. BOUCHAL, M. KRAL, P. BENEŠ a K. SOUCEK. Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition. Carcinogenesis. 2018, -, -. ISSN 0143-3334. IF: 5.072. PMID: 30010814
  • [27]
    SOUCEK, K., A. MALENOVSKA, Z. KAHOUNOVA, J. REMSIK, Z. HOLUBCOVA, T. SOUKUP, D. KURFÜRSTOVÁ, J. BOUCHAL, T. SUCHANKOVA, E. SLABAKOVA a A. HAMPL. Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytes. Journal of Assisted Reproduction and Genetics. 2018, 35(8), 1407-1417. ISSN 1058-0468. IF: 4.406. PMID: 29948426
  • [26]
    FEIERSINGER, G., K. TRATTNIG, P. LEITNER, F. GUGGENBERGER, A. OBERHUBER, S. PEER, M. HERMANN, I. SKVORTSOVA, J. VRBKOVÁ, J. BOUCHAL, Z. CULIG a F.R. SANTER. Olaparib is effective in combination with, and as maintenance therapy after, first-line endocrine therapy in prostate cancer cells. Molecular Oncology. 2018, -, -. ISSN 1574-7891. IF: 5.143. PMID: 29465803
  • [25]
    VONDALOVA BLANAROVA, O., B. SAFARIKOVA, J. HERUDKOVA, M. KRKOSKA, S. TOMANKOVA, Z. KAHOUNOVA, L. ANDERA, J. BOUCHAL, G. KHARAISHVILI, M. KRAL, M. SOVA, A. KOZUBIK a A. HYRSLOVA VACULOVA. Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10. Plos One. 2017, 12(11), e0188584. ISSN 1932-6203. IF: 2.806. PMID: 29182622
  • [24]
    JORDA, R., Z. BUCKOVA, E. ŘEZNÍČKOVÁ, J. BOUCHAL a V. KRYŠTOF. Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81. Biochimica et Biophysica Acta. 2017, 1865(2), 354-363. ISSN 0006-3002. IF: 4.521. PMID: 29157894
  • [23]
    KAHOUNOVA, Z., D. KURFÜRSTOVÁ, J. BOUCHAL, G. KHARAISHVILI, J. NAVRATIL, J. REMSIK, S. SIMECKOVA, V. STUDENT, A. KOZUBIK a K. SOUCEK. The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition. Cytometry A. 2017, -, -. ISSN 1552-4922. IF: 3.181. PMID: 28383825
  • [22]
    ŠVÁCHOVÁ, M., M. TICHÝ, P. FLODR, J. STEIGEROVÁ, Z. KOLÁŘ a J. BOUCHAL. Clonality testing of lymphoproliferative disorders in a large cohort of primary and consultant biopsies. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2017, 161(2), 197-205. ISSN 1213-8118 . IF: 0.924. PMID: 28323289
  • [21]
    GACHECHILADZE, M., J. ŠKARDA, V. KOLEK, I. GRYGÁRKOVÁ, K. LANGOVA, J. BOUCHAL, Z. KOLÁŘ, F. BATY, R. STAHEL, W. WEDER, A. SOLTERMANN a M. JOERGER. Prognostic and predictive value of loss of nuclear RAD51 immunoreactivity in resected non-small cell lung cancer patients. Lung Cancer. 2017, 105, 31-38. ISSN 0169-5002 . IF: 3.767. PMID: 28236982
  • [20]
    STUDENT, V., A. VIDLAR, J. BOUCHAL, J. VRBKOVÁ, Z. KOLÁŘ, M. KRAL, P. KOSINA a J. VOSTALOVA. Cranberry intervention in patients with prostate cancer prior to radical prostatectomy. Clinical, pathological and laboratory findings. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 559-565. ISSN 1213-8118 . IF: 0.894. PMID: 27833172
  • [19]
    ŠIMKOVÁ, D., G. KHARAISHVILI, E. SLABAKOVA, P. MURRAY a J. BOUCHAL. Glycoprotein asporin as a novel player in tumour microenvironment and cancer progression. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 467-473. ISSN 1213-8118 . IF: 0.894. PMID: 27605398
  • [18]
    ŠIMKOVÁ, D., G. KHARAISHVILI, G. KOŘÍNKOVÁ, T. OŽDIAN, T. SUCHANKOVA-KLEPLOVA, T. SOUKUP, M. KŘUPKA, A. GALANDÁKOVÁ, P. DŽUBÁK, M. JANÍKOVÁ, J. NAVRATIL, Z. KAHOUNOVA, K. SOUCEK a J. BOUCHAL. The dual role of asporin in breast cancer progression. Oncotarget. 2016, 7(32), 52045-52060. ISSN 1949-2553 . IF: 5.168. PMID: 27409832
  • [17]
    LUEF, B., F. HANDLE, G. KHARAISHVILI, M. HAGER, J. RAINER, G. JANETSCHEK, S. HRUBY, C. ENGLBERGER, J. BOUCHAL, F.R. SANTER a Z. CULIG. The AR/NCOA1 axis regulates prostate cancer migration by involvement of PRKD1. Endocrine-Related Cancer. 2016, 23(6), 495-508. ISSN 1351-0088. IF: 5.267. PMID: 27255895
  • [16]
    KURFÜRSTOVÁ, D., J. BARTKOVA, R. VRTEL, A. MIČKOVÁ, A. BURDOVA, D. MAJERA, M. MISTRÍK, M. KRAL, F.R. SANTER, J. BOUCHAL a J. BÁRTEK. DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer. Molecular Oncology. 2016, 10(6), 879-894. ISSN 1574-7891. IF: 5.314. PMID: 26987799
  • [15]
    SLABAKOVA, E., G. KHARAISHVILI, M. SMEJOVA, Z. PERNICOVA, T. SUCHANKOVA, J. REMSIK, S. LERCH, N. STRAKOVÁ, J. BOUCHAL, M. KRAL, Z. CULIG, A. KOZUBIK a K. SOUCEK. Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells. Oncotarget. 2015, 6(34), 36156-71. ISSN 1949-2553. IF: 5.008. PMID: 26416355
  • [14]
    BOUCHALOVÁ, K., M. SVOBODA, G. KHARAISHVILI, J. VRBKOVÁ, J. BOUCHAL, R. TROJANEC, V. KOUDELÁKOVÁ, L. RADOVÁ, K. CWIERTKA, M. HAJDÚCH a Z. KOLÁŘ. BCL2 is an independent predictor of outcome in basal-like triple-negative breast cancers treated with adjuvant anthracycline-based chemotherapy. Tumor Biology. 2015, 36(6), 4243-52. ISSN 1010-4283 . IF: 2.926. PMID: 25616695
  • [13]
    BURDOVA, A., J. BOUCHAL, S. TAVANDZIS a Z. KOLÁŘ. TMPRSS2-ERG gene fusion in prostate cancer. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2014, 158(4), 502-510. ISSN 1213-8118. IF: 1.200. PMID: 25485532
  • [12]
    BOUCHALOVÁ, K., G. KHARAISHVILI, J. BOUCHAL, J. VRBKOVÁ, M. HOUDOVÁ MEGOVÁ a A. HLOBILKOVA. Triple negative breast cancer-BCL2 in prognosis and prediction. Review. Current Drug Targets. 2014, 15(12), 1166-1175. ISSN 1389-4501. IF: 3.021. PMID: 25374001
  • [11]
    PERNICOVA, Z., E. SLABAKOVA, R. FEDR, S. SIMECKOVA, J. JAROS, T. SUCHANKOVA, J. BOUCHAL, G. KHARAISHVILI, M. KRAL, A. KOZUBIK a K. SOUCEK. The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells. Molecular Cancer. 2014, 20, 13-113. ISSN 1476-4598. IF: 4.257. PMID: 24884804
  • [10]
    KHARAISHVILI, G., D. ŠIMKOVÁ, K. BOUCHALOVÁ, M. GACHECHILADZE, N. NARSIA a J. BOUCHAL. The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance. Cancer Cell International. 2014, 14(-), Article Number: 41. ISSN 1475-2867. IF: 2.766. PMID: 24883045
  • [9]
    KUCEROVA, R., M. BIENOVA, M. KRAL, J. BOUCHAL, K. TRTKOVA, A. BURDOVA, V. STUDENT a Z. KOLÁŘ. Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. Journal of the European Academy of Dermatology and Venereology. 2015, 29(1), 91-96. ISSN 0926-9959. IF: 3.029. PMID: 24665929
  • [8]
    JAMAPISHVILI, T., M. KRAL, I. KHOMERIKI, V. VYHNANKOVA, G. MGEBRISHVILI, V. STUDENT, Z. KOLÁŘ a J. BOUCHAL. Quadriplex model enhances urine-based detection of prostate cancer. Prostate Cancer and Prostatic Diseases. 2011, 14(4), 354-360. ISSN 1365-7852. IF: 2.421. PMID: 21788966
  • [7]
    KHARAISHVILI, G., M. ČÍŽKOVÁ, K. BOUCHALOVÁ, G. MGEBRISHVILI, Z. KOLÁŘ a J. BOUCHAL. Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study. Journal of Clinical Pathology. 2011, 64(11), 977-982. ISSN 0021-9746. IF: 2.306. PMID: 21742751
  • [6]
    SANTER, F.R., P.P.S. HOSCHELE, S. OH, H.H.E. HOLGER, J. BOUCHAL, I. CAVARRETTA, W. PARSON, D. MEYERS, P.A. COLE a Z. CULIG. Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines. Molecular Cancer Therapeutics. 2011, 10(9), 1644-1655. ISSN 1535-7163. IF: 5.226. PMID: 21709130
  • [5]
    PERNICOVA, Z., E. SLABAKOVA, G. KHARAISHVILI, J. BOUCHAL, M. KRAL, Z. KUNICKA, A. KOZUBIK a K. SOUCEK. Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation Skp2. Neoplasia. 2011, 13(6), 536-536. ISSN 1522-8002. IF: 5.946. PMID: 21677876
  • [4]
    JAMAPISHVILI, T., A. SCORILAS, M. KRAL, I. KHOMERIKI, D. KURFÜRSTOVÁ, Z. KOLÁŘ a J. BOUCHAL. Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients. Neoplasma. 2011, 58(4), 298-303. ISSN 0028-2685. IF: 1.440. PMID: 21520985
  • [3]
    KHARAISHVILI, G., D. ŠIMKOVÁ, E. MAKHAROBLIDZE, K. TRKOVÁ, Z. KOLÁŘ a J. BOUCHAL. WNT signaling in prostate development and carcinogenesis. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2011, 1(55), 11-18. ISSN 1213-8118. IF: 0.702. PMID: 21475372
  • [2]
    BOUCHAL, J., F.R. SANTER, P.P.S. HOSCHELE, E. TOMASTIKOVA, H. NEUWIRT a Z. CULIG. Transcriptional Coactivators p300 and CBP Stimulate Estrogen Receptor-Beta Signaling and Regulate Cellular Events in Prostate Cancer. Prostate. 2011, 71(4), 431-437. ISSN 0270-4137. IF: 3.485. PMID: 20859991
  • [1]
    TURASHVILI, G., J. BOUCHAL, K. BAUMFORTH, W. WEI, M. DZIECHCIARKOVA, J. EHRMANN, J. KLEIN, E. FRIDMAN, J. ŠKARDA, J. SROVNAL, M. HAJDÚCH, P. MURRAY a Z. KOLÁŘ. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. BMC Cancer. 2007, 7(55), -. ISSN 1471-2407. IF: 2.359. PMID: 17389037


Doctoral students mentor:

[3] Alena Mičková, Monitoring characteristics of tumor stem cells from prostate cancer,
Ph.D. specialization: , status: Ongoing, from: 2014
[2] Michaela Šváchová, Importance of molecular markers for cancer diagnostics,
Ph.D. specialization: , status: Graduated, from: 2010 to 2015
[1] Dana Šimková, Study of invasive growth and its blocation possibilities in breast and prostate cancer,
Ph.D. specialization: , status: Graduated, from: 2009 to 2016

Master students mentor:

[1] Kamila Němcová, Checking the integrity of the genome in cancer stem cells of prostate cancer,
status: Graduated, from: 2014 to 2016

Bachelor students mentor:

[1] Silvie Kaločová, Laser microdissection and analysis of selected cell types of prostate cancer,
status: Ongoing, from: 2016