Academic Title: Mgr.
Phone: 585 632 191
Modifications of double bonds in triterpenes with antitumor activity
In this work, double bond of betulin, betulinic acid and other cytotoxic triterpenes will be modified by various methods. First method will be based on transition metal catalyzed crosscoupling reactions, of triterpenic boronic acids with a variety of other molecules. Second, aldehyde will be prepared in the neighborhood of the double bond and it will be condensed with a number of organic hydrazines, hydrazones, amines etc.
Supervisor:Urban Milan Ph.D.
Status:Ongoing 2015 - 2015
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