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Holub Dušan Ph.D.
Academic title:
M.Sc.
E-mail:
dusan.holub@upol.cz
Phone:
+420 585632068, +420 585632069
Groups:
DOCTORAL STUDENT, IMTM, LEM, STAFF
Doctoral training
Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS
Hepcidin, a 25 amino acid peptide, plays an important role in iron homeostasis. As such, it has potential as an indicator of any iron-related condition, such as anemia. My research focuses on the measurement of hepcidin in biological fluids to improve our understanding of iron-related disorders. A possible result of such studies could be the development of hepcidin as a tool for diagnosis and clinical management of such disorders.
Specialization:
Oncology
Supervisor:
Džubák Petr M.D., Ph.D.
Status:
Graduated from 2009 to 2016.
Journals
Evaluation of an integrative Bayesian peptide detection approach on a combinatorial peptide library.
European Journal of Mass Spectrometry.
2022,
27(6),
217-234,
ISSN: 1469-0667,
PMID: 34989269,
Importance of Hepcidin in the Etiopathogenesis of Anemia in Inflammatory Bowel Disease.
Digestive Diseases and Sciences.
2020,
66(10),
3263-3269,
ISSN: 0163-2116,
PMID: 33063192,
Changes in serum hepcidin levels in children with inflammatory bowel disease during anti-inflammatory treatment.
Journal of Paediatrics and Child Health.
2019,
56(2),
276-282,
ISSN: 1034-4810,
PMID: 31411363,