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Telefon: +420 585632069
Skupiny: DOKTORSKÝ STUDENT, IMTM, LEM, PERSONÁL

O mně

Assistant professor at the Institute of Molecular and Translational Medicine. He is involved in drug screening, confocal microscopy and image analysis. His research interests are microtubule targeting agents and mechanisms of resistance to antineoplastic chemotherapy drugs.

Journals

Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Journal of enzyme inhibition and medicinal chemistry. 2024, 39(1), 2367139, ISSN: 1475-6366 , PMID: 38904149,  PDF.
JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR, P. DŽUBÁK
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN: 0045-2068, PMID: 36592487,  PDF.
ŘEHULKA, J., I. SUBTELNA, A. KRYSHCHYSHYN-DYLEVYCH, A. CHERNIIENKO, A. IVANOVA, M. MATVEIEVA, P. POLISHCHUK, S. GURSKÁ, M. HAJDÚCH, O. ZAGRIJTCHUK, P. DŽUBÁK, R. LESYK
Anticancer 5-arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones as tubulin inhibitors. Archiv der Pharmazie. 2022, 355(12), e2200419, ISSN: 0365-6233, PMID: 36109178,