Scientific board meeting – n. 6 PerMed

Scientific board meeting – n. 6 PerMed 

Place: IMTM 
Hněvotínská 1333/5 
779 00 Olomouc 
www.imtm.cz 

Date: 29th March — 30th March 2022

PROGRAM 29th March: 

Particular projects - structure: goals, participants and their role in project, current status, plan for next 6 months. Each project 35 min including discussion. 

• 12:30 - 13:30 LUNCH 
• 13:30 - 13:35 Introductory information – Hajdúch, Fusek 
• 13:35 - 14:10 Janeba - Novel potent inhibitors of purine nucleoside phosphorylase for treatment of T-cell leukemia 
• 14:10 - 14:45 Vyklický - Surface expression, function, and pharmacology of disease-associated mutations in human NMDA receptors – molecular diagnostics and drug development 
• 14:45 - 15:00 COFFEE BREAK 
• 15:00 - 15:30 Maletinská - Anorexigenic and orexigenic peptides for potential treatment of neurodegeneration 
• 15:30 - 17:00 Board meeting (Hajdúch, Fusek, Martásek, Perlík, Hauser, Normanton, Ansorge) 
• 18:00 – 20:00 DINNER (place will be announced) 

PROGRAM 30th March: 

• 09:00 - 09:35 Nencka - New human Constitutive androstane receptor (CAR, NR1I3) ligands for the treatment of metabolic diseases 
• 09:35 - 10:10 Mistrík - Senolytics - cytotoxic therapies for aging cells 
• 10:10 - 10:45 Džubák - Targeted therapy for cells in stress - regulators of oncogenic, ribosomal and/or endoplasmatic stress response 
• 10:45 - 11:00 COFFEE BREAK 
• 11:00 - 11:35 Hajdúch - Gene expression therapeutics - epigenetic and transcriptional regula 
• 11:35 - 12:10 Martásek - Targeted treatment for protein mutation and aggregation diseases - tauopathies, amyloidosis and cancer 
• 12:15 - 13:00 LUNCH