Frydrych Ivo Ph.D.

Journals

BHOGAL, I., I. FRYDRYCH, A. MODI, V. PANKAJ, A. KUMAR, A. KHAIRNAR, V. DAS, S. ROY
Naringenin as a dual-target modulator of RAGE-NF-κB signaling and Aβ fibrillization in Alzheimer's disease: integrated computational and experimental analyses. Frontiers in Pharmacology. 2026, 17, 1901236, ISSN: 1663-9812, PMID: 42712578,  PDF.
BACHOŘÍK, J., I. FRYDRYCH, S. GURSKÁ, S. DOSTAL, J. POKORNÝ, M. HAJDÚCH, M. URBAN
New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products. ACS Omega. 2026, 11(16), 24564-24579, ISSN: 2470-1343, PMID: 42077890,  PDF.
ORSÁG, Š., I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, A. PRIBYLKA, J. HODOŇ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Synthesis and biological evaluation of novel C-30 modified lupane triterpenoids selectively cytotoxic against cancer cells. European Journal of Medicinal Chemistry. 2025, 302 (Pt 1), 118268, ISSN: 0223-5234 , PMID: 41124881,  PDF.

Books & book chapters

FRYDRYCH, I.
Reporters based on luminescence or fluorescence detection , 1.vyd., Olomouc, Palacky University, 2021, 20, 147-152, Dedication: LO1304, ISBN: 978-80-244-6049-9,
FRYDRYCH, I.
Cell cycle analysis by flow cytometry , 1.vyd., Olomouc, Palacky University, 2021, 26, 193-200, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Master mentorship

Reiterová Ivana

Preparation of cell-based reporter assay for high-throughput screening of small molecules as potential receptor for advanced glycation endproducts inhibitors

Status: Graduated from 2015 to 2017.

Bachelor mentorship

Kollárová Ema

Study of biological activity of new betulin derivatives

Status: Graduated from 2023 to 2025.
Šefčíková Pavlína

Biological Activity of Amino Derivatives of Betulin

Status: Ongoing from 2025.