Header image
Hajdúch Marián M.D., Ph.D.
Academic title:
Associate Professor
E-mail:
marian.hajduch@upol.cz
Phone:
+420 585632082, +420 585632083
Groups:
IMTM, LEM, STAFF, SUPERVISOR
About me
Scientist and medical professional mainly involved in molecular and translational medicine (disease area oncology. rare and infectious diseases); long-term experience in project management; R&D and technology transfer activities, including the construction and management of large research infrastructures. Founding director of the Institute of Molecular and Translational Medicine, Palacky University in Olomouc, CZ. He has been involved as principal investigator, investigator or clinical site manager in 19 clinical trials; actively participated in the research and/or management of >50 national and international projects; established Cancer Research Czech Republic as a major charity to support cancer research in CZ; spin-off companies focused on manufacturing of molecular diagnostics, bioinformatics and drug development; leader/co-leader drug development initiatives with one registered drug on market, several products in clinical trials, >35 in vitro diagnostic products on market, several CE IVD certified. Former Chair of the Boards of National Director and current Czech National Director for European Translational Medicine Infrastructure (EATRIS-ERIC); participated in creation of national network for personalized medicine and cancer management policies. Published more than >350 papers, 21 books/chapters, >40 patents, >6700 SCI citations, H-index 41.
Journals
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation.
ACS Omega.
2024,
7(9),
8067-8081,
ISSN: 2470-1343,
PMID: 38405484,
Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic.
European Journal of Public Health.
2024,
ISSN: 1101-1262,
PMID: 38224266,
Books & book chapters
Biologická léčiva: Teoretické základy a klinická praxe,
1. vyd,
Praha,
Grada Publishing,
2012,
219 s,
Dedication: BIOMEDREG CZ.1.05/2.1.00/01.0030,
ISBN: 978-80-247-3727-0,
Detekce nádorových biomarkerů v molekulárně biologické laboratoři,
1. vyd,
Olomouc,
Univerzita Palackého v Olomouci,
2012,
144 s,
Dedication: MOLONKOL CZ.1.07/2.3.00/09.0089,
ISBN: 978-80-244-3002-7,
Význam biomarkerů pro indikaci cílené biologické léčby v onkologii,
1. vyd,
Praha,
Grada Publishing,
2012,
2.8,
137-149,
Dedication: BIOMEDREG CZ.1.05/2.1.00/01.0030,
ISBN: 978-80-247-3727-0,
Intellectual property
1,2-DITHIOLANE COMPOUND FOR METAL SURFACE MODIFICATION (Cígler)
Utility Model: CZ 34573. Granted: 24.11.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HAJDÚCH Marián, JAWOREK Hana, ONDRA Martin, KUBÍČKOVÁ Agáta
Status: Available
N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE FOR TREATMENT OF CIRCADIAN RHYTHM DISEASES, DISORDERS AND DYSFUNCTIONS (Voller)
- Published Application PV 2019-757 under PV 2019-757 (16.6.2021). Ownership: Palacký University Olomouc, Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
- Published Application PCT/CZ2020/050094 under WO 2021/115502 (17.6.2021)
Status: Available
MOLECULAR COMPLEX ASSEMBLY PARTICLES COMRISING BIS-R1, R2-DITHIOCARBAMATE-METAL COMPLEX AND A LIGAND, METHOD OF PREPARATION AND USE THEREOF "DISULFIRAM II" (Mistrík)
- Published Application EP 18199181.1 under EP 3636285 (15.4.2020)
- Published Application PCT/EP2019/077222 under WO 2020/074514 (16.4.2020)
- Patent: AU 2019358428. Granted: 17.11.2022. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: CA 3,114,031. Granted: 12.3.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: IL 281616. Granted: 2.4.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: JP 7220932. Granted: 3.2.2023. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: KR 10-2626651. Granted: 17.1.2024. Ownership: Palacký University Olomouc. Inventors: MISTRÍK Martin, BÁRTEK Jiří, ŠKROTT Zdeněk, DŽUBÁK Petr, HAJDÚCH Marián
Status: Patents pending, Available
Doctoral mentorship
Petrovičová Ivana
Detection of molecular cytogenetic abnormalities
Vojta Petr Ph.D.
Study of genome and transcriptome variability employing data processing from massive parallel DNA sequencing
Status:
Graduated from 2009 to 2018.
Kudlová Natálie M.Sc.
High throughput sequencing methods in biomarker identification and validation
Status:
Graduated from 2014 to 2022.
Open positions
| Project: | Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics |
|---|---|
| Supervisors: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Genetic and epigenetic biomarkers of cancer diseases |
|---|---|
| Supervisors: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D. |
| Available: | 3 |
| Intended for: | Doctoral training |
| Summary: | 3 places in full-time or combined form of study |
| Project: | Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease |
|---|---|
| Supervisors: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development |
|---|---|
| Supervisors: | Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 1 |
| Intended for: | Doctoral training |
| Summary: | 1 place in full-time study |
| Project: | Antitumor drugs targeting nucleic acid metabolism |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Drug repurposing for the treatment and prevention of diseases |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD. |
| Available: | 1 |
| Intended for: | Doctoral training |
| Summary: | 1 place in full-time study |
| Project: | Bioinformatics processing of big data within clinical and preclinical studies |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D. |
| Available: | 3 |
| Intended for: | Doctoral training |
| Summary: | 3 places in full-time or combined form of study |
| Project: | Identification of molecular targets and mechanisms of resistance in antitumor drugs |
|---|---|
| Supervisors: | Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease |
|---|---|
| Supervisors: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Project: | Diagnosis and treatment of rare diseases |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Genetic and epigenetic biomarkers in health and disease |
|---|---|
| Supervisors: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D. |
| Available: | 5 |
| Intended for: | Doctoral training |
| Project: | Physiology and pathophysiology of aging |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Anticancer drugs targeting nucleic acid metabolism |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Project: | Development of drugs in the field of small molecules 2 places in full-time study |
|---|---|
| Supervisors: | Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Summary: | 2 places in full-time study |
| Project: | Identification of proteomic biomarkers in proximal fluids and tissues |
|---|---|
| Supervisors: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Project: | Biologically active molecules and their therapeutic combinations |
|---|---|
| Supervisors: | Hajdúch Marián M.D., Ph.D. |
| Available: | 2 |
| Intended for: | Doctoral training |
| Project: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Supervisors: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| Available: | 5 |
| Intended for: | Doctoral training |