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Skupiny: DOKTORSKÝ STUDENT, EX ZAMĚSTNANCI, IMTM, LIG

Doktorské studium

Molecular mechanisms regulating DNA replication

Specializace: Lékařská genetika
Stav: Absolvoval od 2021 do 2025.

O mně

Doctoral student focused on molecular mechanisms regulating DNA replication and its dynamics, specialized in a method of DNA combing, quantitative image-based cytometry of the immunofluorescence-stained samples with using of ScanR analysis software, and other basic methods (f.e. clonogenic assay, WB).

Journals

DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps. Nature Communications. 2024, 15(1), 7375, ISSN: 2041-1723, PMID: 39191785,  PDF.
Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments. Life Science Alliance. 2022, 5(12), e202201560, ISSN: 2575-1077, PMID: 36260751,

Bachelor mentorship

Najdekova Alica

The role of fork reversal in DNA replication

Stav: Absolvoval od 2023 do 2025.