Contakt

Bajgar Robert M.D., Ph.D.

E-mail: robert.bajgar@upol.cz
Phone: +420 585632106
Curriculum Vitae: download here

I am concerned with the study of cell bioenergetics, questions of mitochondrial processes, ion carriers, generation of reactive oxygen species in normal and tumorous cells exposed to action of physical and chemical factors. I am skilled in a number of biophysical experimental methods including spectroscopic and fluorescence analyses, separation methods of cellular organelles, proteins, nucleic acids, determination of reactive oxygen species, evaluation of cell viability and fluorescence microscopy. Recently I attended a research visit at the Dept. of Biochemistry at the highly respected University of Sao Paulo, where I was familiarized with the novel approaches in the photodynamic studies. I am the author or co-author of more than 30 internationally reviewed papers, several conference communications and 3 patents. My actual h-index is 10.

Publications (Impact Factor Journals)

  • [8]
    BINDER, S., A. HANÁKOVÁ, K. BARTOŇ TOMÁNKOVÁ, K. PÍŽOVÁ, R. BAJGAR, B. MANIŠOVÁ, K. KEJLOVA, H. BENDOVA, D. JIROVA a H. KOLÁŘOVÁ. Adverse Phototoxic Effect of Essential Plant Oils on NIH 3T3 Cell Line after UV Light Exposure. Central European Journal of Public Health. 2016, 24(3), 234-240. ISSN 1210-7778. IF: 0.682. PMID: 27755863
  • [7]
    PÍŽOVÁ, K., R. BAJGAR, R. FILLEROVA, E. KRIEGOVA, V. CENKLOVÁ, K. LANGOVÁ, P. KONEČNÝ a H. KOLÁŘOVÁ. C-MYC and C-FOS expression changes and cellular aspects of the photodynamic reaction with photosensitizers TMPyP and ClAlPcS2. Journal of Photochemistry and Photobiology B: Biology. 2015, 142(-), 186-196. ISSN 1011-1344. IF: 3.035. PMID: 25545333
  • [6]
    BAJGAR, R., H. KOLÁŘOVÁ, L. BOLEK, S. BINDER, K. PÍŽOVÁ a A. HANÁKOVÁ. High Oxygen Partial Pressure Increases Photodynamic Effect on HeLa Cell Lines in the Presence of Chloraluminium Phthalocyanine. Anticancer Research. 2014, 34(8), 4095-4099. ISSN 0250-7005. IF: 1.826. PMID: 25075034
  • [5]
    HANÁKOVÁ, A., K. BOGDANOVÁ, K. TOMÁNKOVÁ, K. PÍŽOVÁ, J. MALOHLAVA, S. BINDER, R. BAJGAR, K. LANGOVÁ, M. KOLÁŘ, J. MOSINGER a H. KOLÁŘOVÁ. The application of antimicrobial photodynamic therapy on S. aureus and E. coli using porphyrin photosensitizers bound to cyclodextrin. Microbiological Research. 2014, 169(2-3), 163-170. ISSN 0944-5013. IF: 2.561. PMID: 23899404
  • [4]
    HANÁKOVÁ, A., K. BOGDANOVÁ, K. TOMÁNKOVÁ, S. BINDER, R. BAJGAR, K. LANGOVÁ, M. KOLÁŘ, J. MOSINGER a H. KOLÁŘOVÁ. Study of photodynamic effects on NIH 3T3 cell line and bacteria. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2014, 158(2), 201-207. ISSN 1213-8118. IF: 1.200. PMID: 23073531
  • [3]
    PÍŽOVÁ, K., K. TOMÁNKOVÁ, A. DAŠKOVÁ, S. BINDER, R. BAJGAR a H. KOLÁŘOVÁ. Photodynamic therapy for enhancing antitumour immunity. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2012, 156(2), 93-102. ISSN 1213-8118. IF: 0.990. PMID: 22837129
  • [2]
    BINDER, S., H. KOLÁŘOVÁ, K. TOMÁNKOVÁ, R. BAJGAR, A. DAŠKOVÁ a J. MOSINGER. Phototoxic effect of TPPS4 and MgTPPS4 on DNA fragmentation of HeLa cells. Toxicology in Vitro. 2011, 25(6), 1169-1172. ISSN 0887-2333. IF: 2.775. PMID: 21078379
  • [1]
    BINDER, S., H. KOLÁŘOVÁ, R. BAJGAR, K. TOMÁNKOVÁ a A. DAŠKOVÁ. In vitro application of porphyrin photosensitisers on MCF7, HeLa and G361 tumour cell lines. European Biophysics Journal with Biophysics Letters. 2011, 40(1), 39-39. ISSN 0175-7571. IF: 2.139.
  • Publications (Other Reviewed Journals)

  • [3]
    BAJGAR, R., H. KOLÁŘOVÁ, S. BINDER, A. DASKOVA, H. LENOBELOVA, K. PÍŽOVÁ a K. TOMÁNKOVÁ. Imunofluorescenční analýza proapoptotických signálních molekul v buňkách lidského melanomu po fotodynamické terapii. Lékař a technika. 2013, 43(1), 15-18. ISSN 0301-5491.
  • [2]
    HANÁKOVÁ, A., K. BOGDANOVÁ, K. TOMÁNKOVÁ, K. PÍŽOVÁ, J. MALOHLAVA, S. BINDER, R. BAJGAR, K. LANGOVÁ, M. KOLÁŘ, J. MOSINGER a H. KOLÁŘOVÁ. Fototoxický vliv porfyrinových sensitizerů a viditelného záření na gram-pozitivní methicilin-rezistentní kmen S. aureus. Lékař a technika. 2013, 43(1), 19-23. ISSN 0301-5491.
  • [1]
    PÍŽOVÁ, K., K. TOMÁNKOVÁ, K. LANGOVÁ, A. HANÁKOVÁ, H. LENOBELOVA, H. ZAPLETALOVÁ, J. MALOHLAVA, S. BINDER, R. BAJGAR, J. VACHUTKA, L. DOLEŽAL a H. KOLÁŘOVÁ. Vliv ultrazvuku na účinnost fotodynamické terapie - in vitro studie. Lékař a technika. 2012, 42(4), 18-22. ISSN 0301-5491.

  • Patents, Utility models & other IP's :

    [5] FLAT RADIATING SOURCE, PARTICULARLY FOR IN VITRO INDUCING AND MONITORING PHOTODYNAMIC PHENOMENON, PV 2015-330
    1. Patent: CZ 305 993, Granted: 27. 4. 2016, Ownership: Palacky University Olomouc, Inventors: Bajgar RobertKolářová Hana, Kolář Petr, Pížová Klára, Hanáková Adéla
    2. Published Application PCT/CZ2015/000125 under WO 2016/184441

    Status: Available

    [4] MOBILE HYPERBARIC MINIATURE CHAMBER, Priority Appl. CZ PV 2014-812
    1. Patent: CZ 305 989, Granted: 27. 4. 2016, Ownership: Palacky University Olomouc, Inventors: Kolářová HanaBajgar Robert, Tománková Kateřina, Bolek Lukáš, Dejmek Jiří, Bolek Matouš, Růžička Jiří, Beneš Jiří
    2. Utility Model: PUV 2014-30305, CZ 27 799, Granted: 6. 2. 2015, Ownership: Palacky University Olomouc, Inventors: Kolářová HanaBajgar Robert, Tománková Kateřina, Bolek Lukáš, Dejmek Jiří, Bolek Matouš, Růžička Jiří, Beneš Jiří

    Status: Available

    [3] LIGHT SOURCE INTENDED PARTICULARY FOR IN VITRO CREATING AND MONITORING PHOTODYNAMIC PHENOMENA, Priority Appl. CZ PUV 2015-31095
    1. Utility Model: CZ 28 377, Granted: 23. 6. 2015, Ownership: Palacky University Olomouc, Inventors: Bajgar RobertKolářová Hana, Kolář Petr, Pížová Klára, Hanáková Adéla

    Status: Available 

    [2] LIGHT SOURCE OF UNIFORM ENERGY DENSITY TO INDUCE PHOTODYNAMIC PHENOMENA IN VITRO CELLS, Priority Appl. CZ PV 2006-813
    1. Patent: CZ 302 829, Granted: 19. 10. 2011, Ownership: Palacky University Olomouc, Inventors: Tomečka Marek, Bajgar RobertKolářová Hana

    Status: Terminated

    [1] LIGHT SOURCE WITH LUMINOUS FIELD HOMOGENEITY, ESPECIALLY FOR INDUCING AND MONITORING PHOTODYNAMIC PHENOMENON IN VITRO, Priority Appl. CZ PV 2009-863
    1. Patent: CZ 302 084, Granted: 20. 8. 2010, Ownership: Palacky University Olomouc, Inventors: Bajgar Robert, Kolářová Hana
    2. Patent: SK 288148, Granted: 13. 11. 2013, Ownership: Palacky University Olomouc,  Inventors: Bajgar Robert, Kolářová Hana

    Status: Terminated


    Doctoral students mentor:

    [1] Martin Pola, The role of oxygen in the effectiveness of photodynamic therapy on cellular models in the presence of sensitizers,
    Ph.D. specialization: , status: Ongoing, from: 2015