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Najdekr Lukáš Ph.D.

Journals

BEGER, R., R. GOODACRE, C. JONES, K. LIPPA, O. MAYBORODA, D. O´NEILL, L. NAJDEKR, I. NTAI, I. WILSON, W. DUNN
Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial. Metabolomics. 2024, 20(5), 95, ISSN: 1573-3882, PMID: 39110307,  PDF.
NASH, W., J. NGERE, L. NAJDEKR, W. DUNN
Characterization of Electrospray Ionization Complexity in Untargeted Metabolomic Studies. Analytical Chemistry. 2024, ISSN: 0003-2700, PMID: 38917347.  PDF.
KVASNIČKA, A., L. NAJDEKR, D. DOBEŠOVÁ, B. PISKLÁKOVÁ, E. IVANOVOVÁ, D. FRIEDECKÝ
Clinical lipidomics in the era of the big data. Clinical Chemistry and Laboratory Medicine. 2023, 61(4), 587-598, ISSN: 1434-6621, PMID: 36592414,  PDF.

Doctoral mentorship

Macháň Jan

Application of open-source software approaches for analyses of clinical metabolmics and lipidomics data

Stav: Probíhající od 2023.
Masař Richard

Lipidomic and proteomic biomarkers of cancer

Stav: Probíhající od 2024.

Master mentorship

Mádrová Lucie M.Sc

Usage of lipid profile for study of inherited metabolic disorders

Stav: Absolvoval od 2013 do 2015.
Filipová Sára

Metabolomic characterisation of endometriosis

Stav: Probíhající od 2023.
Masař Richard

Lipidomic profiling of cardiovascular disease

Stav: Absolvoval od 2021 do 2024.

Bachelor mentorship

Boyko Daniel

Targeted metabolomics of transgenic mice suffering from LPS-induced neuroinflammation

Stav: Absolvoval od 2017 do 2018.
Filipová Sára

Analysis of omega-3 fatty acid from fish extracts

Stav: Absolvoval od 2021 do 2023.
Masař Richard

Development and validation of LC/MS assay for analyses of fat-soluble vitamins

Stav: Absolvoval od 2021 do 2022.

Open positions

Projekt: Application of untargeted lipidomics and metabolomics as a tool for generating hypotheses in personalized medicine
Vedoucí: Najdekr Lukáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Applied lipidomics approach in the search for new clinical biomarkers and elucidation of the structure of unknown lipid species
Vedoucí: Najdekr Lukáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Use of open-source software approaches for analysis of metabolomic and lipidomic clinical data
Vedoucí: Najdekr Lukáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Projekt: Isolation and analysis of membrane lipid rafts using a non-targeted metabolomics and lipidomics approach
Vedoucí: Najdekr Lukáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Projekt: Vitamin analysis in human plasma cohort by application of UHPLC-MS
Vedoucí: Najdekr Lukáš Ph.D.
K dispozici: 1
Určeno pro: Bakalářské studium
Souhrn: Description: The main goal would be to learn basic analytical skills in the metabolomics laboratory. Starting with sample preparation (different types of extractions), followed by data acquisition on the LCMS analytical platform. The last step is a biological interpretation of measured data; in this case, the effects of vitamin deficiency or overdose on the human organism.