Academic Title: PharmDr.
E-mail:
alice.nova@upol.cz
Phone:
+420 585632334, +420 585632244
Groups:
LEM, Exstaff
Curriculum Vitae:
alice_nova_cv-en.pdf
About me
Researcher experienced in the field of early ADME (absorption, distribution, metabolism and excretion) profiling of drug candidates.Research interests: determination of in vitro ADME properties of NCEs (new chemical entities), i.e. assessment of NCEs GIT permeability, identification of P-glycoprotein substrates, prediction of blood brain barrier permeability, determination of chemical and metabolic stability, determination of the NCEs stability in plasma, determination of NCEs plasma protein binding.Published 5 scientific papers, 20 SCI citations, H-index 2. Publications:Techlovská S, Chambers JN, Dvořáková M, Petralia RS, Wang YX, Hájková A, Nová A, Franková D, Prezeau L, Blahoš J. Metabotropic glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in mGluR1a/b dimers in vivo. Neuropharmacology. 2014, 86, 329-36. ISSN: 0028-3908. IF (2013): 4.819. PMID: 25158311Rulcova A, Krausova L, Smutny T, Vrzal R, Dvorak Z, Jover R, Pavek P. Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes. Pharmacol Rep. 2013, 65(5), 1322-35. ISSN: 1734-1140. IF (2012): 1,965. PMID: 24399729Rulcova A, Prokopova I, Krausova L, Bitman M, Vrzal R, Dvorak Z, Blahos J, Pavek P. Stereoselective interactions of warfarin enantiomers with Pregnane X nuclear (PXR) receptor in gene regulation of major drug-metabolizing cytochrom P450 enzymes. J Thromb Haemost. 2010, 8(12), 2708-17. ISSN: 1538-7933. IF (2009): 6,069. PMID: 20735727
[{{ impactedPublicationsCount - key }}]
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ publication.title }},
{{ publication.periodical }},
{{ publication.released | amFromUnix | amDateFormat:'YYYY' }},
{{ publication.volume }},
{{ publication.page_range }},
{{ publication.issn }},
IF: {{ publication.if }},
PMID: {{ publication.pmid }}.
[{{ nonifPublicationsCount - key }}]
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ publication.title }},
{{ publication.periodical }},
{{ publication.released | amFromUnix | amDateFormat:'YYYY' }},
{{ publication.volume }},
{{ publication.page_range }},
{{ publication.issn }},.
PMID: {{ publication.pmid }}.
[{{ booksCount - key }}]
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ book.title }},
{{ book.edition }},
{{ book.place_of_publication }}: {{ book.publisher }},
{{ book.released | amFromUnix | amDateFormat:'YYYY' }},
{{ book.pages }} s,
ISBN: {{ book.isbn }}.
[{{ bookChaptersCount - key }}]
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ author.first_name | uppercase | limitTo:1 }}. {{ author.last_name | uppercase }},
{{ book.title }} in {{ book.book_title }},
{{ book.edition }},
{{ book.place_of_publication }}: {{ book.publisher }},
{{ book.released | amFromUnix | amDateFormat:'YYYY' }},
Chapter: {{ book.number }},
Pages: {{ book.page_range }},
ISBN: {{ book.isbn }}.
[{{ intelectualPropertyCount - key }}] {{ property.title }}, Priority Appl. {{ property.priority_application }}
{{ student.first_name }} {{ student.last_name }} {{ student.degree }}
Spacialization: {{ student.specialization }}
Status: {{ student.status }}. from .
{{ student.first_name }} {{ student.last_name }} {{ student.degree }}
Spacialization: {{ student.specialization }}.
Status: {{ student.status }}. from .
{{ student.first_name }} {{ student.last_name }} {{ student.degree }}
Status: {{ student.status }}. from .
{{ student.first_name }} {{ student.last_name }} {{ student.degree }}
Status: {{ student.status }}. from .
| Project: | {{ topic.label }} |
|---|---|
| Supervisors: | {{ supervisor.fullname }}, |
| Available: | {{ topic.positions }} |
| Intended for: | {{ topic.training.join(', ') }} |
| Summary: |