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Borková Lucie Ph.D.

Academic Title: M.Sc.
Phone: +420 585632183
Groups: Doctoral Student, Exstaff, Master Student

Doctoral training

Modification of triterpenes with the use of transition metal catalyzed reactions and nucleophilic substitution.

In this work, a larger study of transition metal catalyzed reaaction of triterpenes should be studied in order to find a new approach for a preparation of novel derivatives with high cytotoxic activity and favorable pharmacological properties.

Supervisor: Urban Milan Ph.D.
Specialization: Organic chemistry.
Status: Graduated from 2014 to 2018.

Master training

Modification of the position 2 in betulin, allobetulin and betulinic acid with polar substituents.

The main aim of the study is to modify lupane and 18-αoleanane triterpenoids in order to obtain a set of new derivatives with higher cytotoxicity and better solubility than the starting material.

Supervisor: Urban Milan Ph.D.
Status: Graduated from 2012 to 2014.
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