Doctoral training
Effect and toxicity of HIPEC.
Bachelor training
Gallium-68 labelled RGD peptides for PET imaging of glioblastoma multiforme.
RGD peptides are accumulated in tumors expressing αvβ3 integrin (marker of angiogenesis). This thesis will include radiolabelling of selected RGD peptides. Peptide derivatives will be passed to in vitro tests employing cell line U-87 MG (glioblastoma multiforme) to assess their ability to bind to tumor cells. Finally the appropriate candidates will be used for in vivo imaging of glioma in mouse model. The imaging will be carried out in microPET/CT system and its results will be compared with ex vivo biodistribution study.
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