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Flašarová Dominika

Groups: ONKOLOGIE, Bachelor Student, Doctoral Student, Master Student, Staff

Doctoral training

Effect and toxicity of HIPEC.

Specialization: Oncology.
Status: Ongoing from 2018.

Bachelor training

Gallium-68 labelled RGD peptides for PET imaging of glioblastoma multiforme.

RGD peptides are accumulated in tumors expressing αvβ3 integrin (marker of angiogenesis). This thesis will include radiolabelling of selected RGD peptides. Peptide derivatives will be passed to in vitro tests employing cell line U-87 MG (glioblastoma multiforme) to assess their ability to bind to tumor cells. Finally the appropriate candidates will be used for in vivo imaging of glioma in mouse model. The imaging will be carried out in microPET/CT system and its results will be compared with ex vivo biodistribution study.

Supervisor: Nový Zbyněk Ph.D.
Status: Graduated from 2015 to 2016.
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